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Published peptide research references

Semaglutide

Governed registry record

25 approved source records with original-source links. Source verification confirms the reference and its connection to this record; it does not certify every scientific conclusion or establish safety or efficacy.

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Approved source records

  1. WEGOVY (semaglutide) prescribing information, revised June 2026

    2026

  2. Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity.

    W Timothy Garvey, Matthias Blüher, Cynthia Karenina Osorto Contreras, Melanie J Davies, Eva Winning Lehmann, Kirsi H Pietiläinen, Domenica Rubino, Paolo Sbraccia · 2025

    DOI: 10.1056/NEJMoa2502081PMID: 40544433

  3. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial.

    Christian S Hendershot, Michael P Bremmer, Michael B Paladino, Georgios Kostantinis, Thomas A Gilmore, Neil R Sullivan, Amanda C Tow, Sarah S Dermody · 2025

    DOI: 10.1001/jamapsychiatry.2024.4789PMID: 39937469

  4. Once-weekly semaglutide 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial.

    Sean Wharton, Paula Freitas, Jøran Hjelmesæth, Maria Kabisch, Kristian Kandler, Ildiko Lingvay, Maria Quiroga, Julio Rosenstock · 2025

    DOI: 10.1016/S2213-8587(25)00226-8PMID: 40961952

  5. Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes.

    Darren K McGuire, Nikolaus Marx, Sharon L Mulvagh, John E Deanfield, Silvio E Inzucchi, Rodica Pop-Busui, Johannes F E Mann, Scott S Emerson · 2025

    DOI: 10.1056/NEJMoa2501006PMID: 40162642

  6. Tirzepatide as Compared with Semaglutide for the Treatment of Obesity.

    2025

    DOI: 10.1056/NEJMoa2416394PMID: 40353578

  7. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes

    2024

    DOI: 10.1056/NEJMoa2403347PMID: 38785209

  8. Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Patients Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Areesha Moiz, Jeremy Y Levett, Kristian B Filion, Katya Peri, Pauline Reynier, Mark J Eisenberg · 2024

    DOI: 10.1016/j.amjcard.2024.04.041PMID: 38679221

  9. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis.

    Henning Bliddal, Harold Bays, Sébastien Czernichow, Joanna Uddén Hemmingsson, Jøran Hjelmesæth, Thomas Hoffmann Morville, Anna Koroleva, Jesper Skov Neergaard · 2024

    DOI: 10.1056/NEJMoa2403664PMID: 39476339

  10. Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial

    2023

    DOI: 10.1016/S0140-6736(23)01185-6PMID: 37385278

  11. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes

    2023

    DOI: 10.1056/NEJMoa2307563PMID: 37952131

  12. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial

    2022

    DOI: 10.1001/jama.2021.23619PMID: 35015037

  13. Efficacy and Safety of Semaglutide for Weight Loss in Obesity Without Diabetes: A Systematic Review and Meta-Analysis.

    2022

    DOI: 10.15605/jafes.037.02.14PMID: 36578889

  14. Once-Weekly Semaglutide in Adolescents with Obesity

    2022

    DOI: 10.1056/NEJMoa2208601PMID: 36322838

  15. Semaglutide 2.4 mg once a week in adults from east Asia with overweight or obesity, with or without type 2 diabetes (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a trial

    2022

    DOI: 10.1016/S2213-8587(22)00008-0PMID: 35131037

  16. Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial

    2022

    DOI: 10.1038/s41591-022-02026-4PMID: 36216945

  17. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension.

    2022

    DOI: 10.1111/dom.14725PMID: 35441470

  18. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial

    2021

    DOI: 10.1001/jama.2021.3224PMID: 33755728

  19. Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity: The STEP 3 Randomized Clinical Trial

    2021

    DOI: 10.1001/jama.2021.1831PMID: 33625476

  20. Efficacy and safety of once-weekly semaglutide 2.0 mg versus 1.0 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, phase 3B trial

    2021

    DOI: 10.1016/S2213-8587(21)00174-1PMID: 34293304

  21. Once-Weekly Semaglutide in Adults with Overweight or Obesity.

    2021

    DOI: 10.1056/NEJMoa2032183PMID: 33567185

  22. Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial.

    2021

    DOI: 10.1016/S0140-6736(21)00213-0PMID: 33667417

  23. Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

    2019

    DOI: 10.1056/NEJMoa1901118PMID: 31185157

  24. The Discovery and Development of Liraglutide and Semaglutide.

    2019

    DOI: 10.3389/fendo.2019.00155PMID: 31031702

  25. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

    2016

    DOI: 10.1056/NEJMoa1607141PMID: 27633186