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Published peptide research references

Thymosin beta-4

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72 approved source records with original-source links. Source verification confirms the reference and its connection to this record; it does not certify every scientific conclusion or establish safety or efficacy.

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Approved source records

  1. Thymosin Beta-4 and Ciprofloxacin Adjunctive Therapy Improves <i>Pseudomonas aeruginosa</i>-Induced Keratitis.

    DOI: 10.3390/cells7100145PMID: 30241380

    Source identity and connection checked by Codex (AI).

  2. Thymosin Beta-4 and TB-500 in Tissue Healing, Regeneration, and Musculoskeletal Repair: A Scoping Review

    DOI: 10.20944/preprints202605.1124.v1

    Source identity and connection checked by Codex (AI).

  3. Decidualization-empowered ECM hydrogel integrating sustained Tβ4 release drives endometrial regeneration in intrauterine adhesions.

    2026

    DOI: 10.1038/s41467-026-68677-wPMID: 41565687

  4. Reparative Outcomes in Corneal Infection: Linking Adjunctive Tβ4 Treatment to Nerve Regeneration and Visual Function.

    2026

    DOI: 10.1167/iovs.67.6.22PMID: 42283548

  5. Enhancing fat graft survival: thymosin beta-4 facilitates mitochondrial transfer from ADSCs via tunneling nanotubes by upregulating the Rac/F-actin pathway.

    2025

    DOI: 10.1016/j.freeradbiomed.2024.12.061PMID: 39761767

  6. Mechanistic study of the Tβ4/SLC7A11 signaling pathway regulating breast cancer evolution.

    2025

    DOI: 10.1016/j.cellsig.2025.112111PMID: 40912522

  7. Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult Mammals.

    2025

    DOI: 10.3390/ijms26094131PMID: 40362372

  8. Tβ4-17 peptide enhances the chemo-sensitivity of ovarian cancer cells to DDP by affecting NF-κB signaling pathway.

    2025

    DOI: 10.1007/s12032-025-03106-4PMID: 41205079

  9. Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.

    2025

    DOI: 10.1002/advs.202505009PMID: 40279568

  10. Activation of pro-resolving pathways mediate the therapeutic effects of thymosin beta-4 during <i>Pseudomonas aeruginosa</i>-induced keratitis.

    2024

    DOI: 10.3389/fimmu.2024.1458684PMID: 39380984

  11. Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice.

    2024

    DOI: 10.1016/j.yexcr.2023.113871PMID: 38049080

  12. A Novel Combination Therapy Tβ4/VIP Protects against Hyperglycemia-Induced Changes in Human Corneal Epithelial Cells.

    2023

    DOI: 10.3390/bios13110974PMID: 37998149

  13. Detection and quantification of the metabolite Ac-Tβ<sub>1-14</sub> in in vitro experiments and urine of rats treated with Ac-Tβ4: A potential biomarker of Ac-Tβ4 for doping tests.

    2023

    DOI: 10.1002/dta.3552PMID: 37515313

  14. Targeted heart repair by Tβ4-loaded cardiac-resident macrophage-derived extracellular vesicles modified with monocyte membranes.

    2023

    DOI: 10.1016/j.actbio.2023.08.022PMID: 37597679

  15. Thymosin beta-4 - A potential tool in healing middle ear lesions in adult mammals.

    2023

    DOI: 10.1016/j.intimp.2023.109830PMID: 38706788

  16. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies.

    2023

    DOI: 10.1016/j.intimp.2023.109741PMID: 36709593

  17. Thymosin beta-4 participate in antibacterial immunity and wound healing in black tiger shrimp, Penaeus monodon.

    2023

    DOI: 10.1016/j.fsi.2023.109065PMID: 37689229

  18. Aberrant Expression of Thymosin Beta-4 Correlates With Advanced Disease and BRAF V600E Mutation in Thyroid Cancer.

    2022

    DOI: 10.1369/00221554221138370PMID: 36321670

  19. Nuclear factor (erythroid-derived 2)-like 2 counter-regulates thymosin beta-4 expression and primary cilium formation for HeLa cervical cancer cell survival.

    2022

    DOI: 10.1038/s41598-022-24596-6PMID: 36424462

  20. Recombinant Human Thymosin β4 (rhTβ4) Modulates the Anti-Inflammatory Responses to Alleviate Benzalkonium Chloride (BAC)-Induced Dry Eye Disease.

    2022

    DOI: 10.3390/ijms23105458PMID: 35628276

  21. The Role of Tβ4-POP-Ac-SDKP Axis in Organ Fibrosis.

    2022

    DOI: 10.3390/ijms232113282PMID: 36362069

  22. Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells.

    2022

    DOI: 10.1186/s13287-021-02687-xPMID: 35012642

  23. Adjunctive Thymosin Beta-4 Treatment Influences MΦ Effector Cell Function to Improve Disease Outcome in <i>Pseudomonas aeruginosa</i>-Induced Keratitis.

    2021

    DOI: 10.3390/ijms222011016PMID: 34681676

  24. Adjunctive Thymosin Beta-4 Treatment Influences PMN Effector Cell Function during <i>Pseudomonas aeruginosa</i>-Induced Corneal Infection.

    2021

    DOI: 10.3390/cells10123579PMID: 34944086

  25. Association between Thymosin beta-4, acute kidney injury, and mortality in patients with sepsis: An observational cohort study.

    2021

    DOI: 10.1016/j.intimp.2021.108167PMID: 34607232

  26. Circular RNA PIP5K1A (circPIP5K1A) accelerates endometriosis progression by regulating the miR-153-3p/Thymosin Beta-4 X-Linked (TMSB4X) pathway.

    2021

    DOI: 10.1080/21655979.2021.1978618PMID: 34546850

  27. Di-(2-ethylhexyl) phthalate-induced tumor growth is regulated by primary cilium formation via the axis of H<sub>2</sub>O<sub>2</sub> production-thymosin beta-4 gene expression.

    2021

    DOI: 10.7150/ijms.53595PMID: 33526986

  28. In vivo CRISPR-Cas9 knockout screening using quantitative PCR identifies thymosin beta-4 X-linked that promotes diffuse-type gastric cancer metastasis.

    2021

    DOI: 10.1002/mc.23326PMID: 34081824

  29. Recombinant Human Thymosin Beta-4 Protects against Mouse Coronavirus Infection.

    2021

    DOI: 10.1155/2021/9979032PMID: 33967626

  30. Recombinant human thymosin beta-4 (rhTβ4) improved scalp condition and microbiome homeostasis in seborrheic dermatitis.

    2021

    DOI: 10.1111/1751-7915.13897PMID: 34318587

  31. Thymosin beta-4 prenatal administration improves fetal development and halts side effects due to preterm delivery.

    2021

    DOI: 10.26355/eurrev_202101_24411PMID: 33506933

  32. Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State-New Directions in Anti-Aging Regenerative Therapies.

    2021

    DOI: 10.3390/cells10061343PMID: 34071596

  33. Antimicrobial Effects of Thymosin Beta-4 and Ciprofloxacin Adjunctive Therapy in <i>Pseudomonas aeruginosa</i> Induced Keratitis.

    2020

    DOI: 10.3390/ijms21186840PMID: 32961846

  34. Electrospun thymosin Beta-4 loaded PLGA/PLA nanofiber/ microfiber hybrid yarns for tendon tissue engineering application.

    2020

    DOI: 10.1016/j.msec.2019.110268PMID: 31753373

  35. Transplantation of Endothelial Progenitor Cells in Obese Diabetic Rats Following Myocardial Infarction: Role of Thymosin Beta-4.

    2020

    DOI: 10.3390/cells9040949PMID: 32290541

  36. Expression and localisation of thymosin beta-4 in the developing human early fetal heart.

    2018

    DOI: 10.1371/journal.pone.0207248PMID: 30412598

  37. Highly effective biosynthesis of N-acetylated human thymosin β4 (Tβ4) in Escherichia coli.

    2018

    DOI: 10.1080/21691401.2018.1489268PMID: 29989423

  38. No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart.

    2018

    DOI: 10.1002/prp2.407PMID: 29864245

  39. Sources of variability in quantifying circulating thymosin beta-4: literature review and recommendations.

    2018

    DOI: 10.1080/14712598.2018.1448382PMID: 29502471

  40. Global Proteomics-based Identification and Validation of Thymosin Beta-4 X-Linked as a Prognostic Marker for Head and Neck Squamous Cell Carcinoma.

    2017

    DOI: 10.1038/s41598-017-09539-wPMID: 28831179

  41. Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction.

    2017

    DOI: 10.1161/jaha.117.005586PMID: 28611096

  42. Thymosin beta-4 overexpression correlates with high-risk groups in gastric gastrointestinal stromal tumors: A retrospective analysis by immunohistochemistry.

    2017

    DOI: 10.1016/j.prp.2017.07.005PMID: 28756979

  43. Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.

    2017

    DOI: 10.1038/s41598-017-03782-xPMID: 28630423

  44. Tβ4-overexpression based on the piggyBac transposon system in cashmere goats alters hair fiber characteristics.

    2017

    DOI: 10.1007/s11248-016-9988-7PMID: 27900536

  45. A thymosin beta-4 is involved in production of hemocytes and immune defense of Hong Kong oyster, Crassostrea hongkongensis.

    2016

    DOI: 10.1016/j.dci.2015.12.007PMID: 26695126

  46. Function of Thymosin Beta-4 in Ethanol-Induced Microglial Activation

    2016

    DOI: 10.1159/000445578PMID: 27189760

  47. Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.

    2016

    DOI: 10.1371/journal.pone.0146708PMID: 26789270

  48. Expression of thymosin beta-4 in human periodontal ligament cells and mouse periodontal tissue and its role in osteoblastic/cementoblastic differentiation.

    2015

    DOI: 10.1016/j.diff.2015.08.003PMID: 26361868

  49. Hypoxia/reoxygenation-experienced cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of thymosin beta-4.

    2015

    DOI: 10.18632/oncotarget.3218PMID: 25888632

  50. MALDI-imaging reveals thymosin beta-4 as an independent prognostic marker for colorectal cancer.

    2015

    DOI: 10.18632/oncotarget.6103PMID: 26556858

  51. Thymosin Beta-4 Induces Mouse Hair Growth.

    2015

    DOI: 10.1371/journal.pone.0130040PMID: 26083021

  52. Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence.

    2015

    DOI: 10.4103/0366-6999.157686PMID: 26021512

  53. In vivo growth suppression of CT-26 mouse colorectal cancer cells by adenovirus-expressed small hairpin RNA specifically targeting thymosin beta-4 mRNA.

    2014

    DOI: 10.1038/cgt.2014.43PMID: 25124811

  54. The actin-sequestering protein thymosin beta-4 is a novel target of hypoxia-inducible nitric oxide and HIF-1α regulation.

    2014

    DOI: 10.1371/journal.pone.0106532PMID: 25271630

  55. Thymosin beta-4 knockdown in IEC-6 normal intestinal epithelial cells induces DNA re-replication via downregulating Emi1.

    2014

    DOI: 10.1002/jcp.24609PMID: 24615569

  56. Cellular trafficking of thymosin beta-4 in HEPG2 cells following serum starvation.

    2013

    DOI: 10.1371/journal.pone.0067999PMID: 23967050

  57. Identification of tubulin beta chain, thymosin beta-4-like protein 3, and cytochrome b-c₁ complex subunit 1 as serological diagnostic biomarkers of gastric cancer.

    2013

    DOI: 10.1016/j.clinbiochem.2013.05.068PMID: 23747515

  58. Multiple functional involvement of thymosin beta-4 in tooth germ development.

    2013

    DOI: 10.1007/s00418-012-1033-1PMID: 23052839

  59. Thymosin beta-4 promotes mesenchymal stem cell proliferation via an interleukin-8-dependent mechanism.

    2013

    DOI: 10.1016/j.yexcr.2013.04.014PMID: 23712052

  60. Regulation of glycogen synthase kinase-3 by thymosin beta-4 is associated with gastric cancer cell migration.

    2012

    DOI: 10.1002/ijc.27490PMID: 22328534

  61. Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1α stabilization in HeLa human cervical tumor cells

    2010

    DOI: 10.1016/j.lfs.2010.07.002PMID: 20637781

  62. Actin-sequestering protein, thymosin beta-4, is a novel hypoxia responsive regulator.

    2010

    DOI: 10.1007/s10585-010-9350-zPMID: 20821256

  63. Effect of toll-like receptor activation on thymosin beta-4 production by chicken macrophages.

    2010

    DOI: 10.1007/s11010-010-0528-0PMID: 20614231

  64. Protection of thymosin beta-4 on corneal endothelial cells from UVB-induced apoptosis.

    2010

    DOI: 10.4077/cjp.2010.amh091PMID: 21793328

  65. Thymosin beta-4 directs cell fate determination of human mesenchymal stem cells through biophysical effects.

    2010

    DOI: 10.1002/jor.20956PMID: 19637215

  66. Hypoxia-inducible transcription factor (HIF)-1 alpha stabilization by actin-sequestering protein, thymosin beta-4 (TB4) in Hela cervical tumor cells.

    2008

    DOI: 10.1016/j.canlet.2008.01.004PMID: 18272284

  67. Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage

    2008

    DOI: 10.1136/bjo.2007.136747PMID: 18480304

  68. Identification and characterization of thymosin beta-4 in chicken macrophages using whole cell MALDI-TOF.

    2007

    DOI: 10.1196/annals.1415.028PMID: 17947593

  69. Localization of thymosin beta-4 in tumors.

    2007

    DOI: 10.1196/annals.1415.005PMID: 17495241

  70. Selective nonsteroidal anti-inflammatory drugs induce thymosin beta-4 and alter actin cytoskeletal organization in human colorectal cancer cells.

    2004

    DOI: 10.1124/jpet.104.070664PMID: 15292456

  71. Expression of thymosin beta-4 and related genes in developing human brain

    1992

    DOI: 10.1007/bf02919408PMID: 1627460

  72. Possibility of HIV gp41 and thymosin beta-4 sharing the same antigenic epitope

    1989

    DOI: 10.1097/00002030-198905000-00013PMID: 2475143