Published peptide research references
Hexarelin
Governed registry record
27 approved source records with original-source links. Source verification confirms the reference and its connection to this record; it does not certify every scientific conclusion or establish safety or efficacy.
Open the peptide evidence profile →Approved source records
Growth hormone-releasing peptides.
Source identity and connection checked by Codex (AI).
Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases.
DOI: 10.1007/s12020-015-0531-z
Source identity and connection checked by Codex (AI).
Hexarelin attenuates abdominal aortic aneurysm formation by inhibiting SMC phenotype switch and inflammasome activation.
Bo Jiang; Mo Wang; Xue Li; Pengwei Ren; Guangxin Li; Yuqi Wang; Lei Wang; Xuan Li; Dong Yang; Lingfeng Qin; Shijie Xin · Microvascular research · 2022
Ghrelin receptor agonist hexarelin attenuates antinociceptive tolerance to morphine in rats.
Tayfun Baser; Ercan Ozdemir; Ahmet Kemal Filiz; Ahmet Sevki Taskiran; Sinan Gursoy · Canadian journal of physiology and pharmacology · 2021
Hexarelin Modulation of MAPK and PI3K/Akt Pathways in Neuro-2A Cells Inhibits Hydrogen Peroxide-Induced Apoptotic Toxicity.
Ramona Meanti; Laura Rizzi; Elena Bresciani; Laura Molteni; Vittorio Locatelli; Silvia Coco; Robert John Omeljaniuk; Antonio Torsello · Pharmaceuticals (Basel, Switzerland) · 2021
Hexarelin modulates lung mechanics, inflammation, and fibrosis in acute lung injury.
Vanessa Zambelli; Laura Rizzi; Paolo Delvecchio; Elena Bresciani; Emanuele Rezoagli; Laura Molteni; Ramona Meanti; Maria Serena Cuttin; Giorgio Bovo; Silvia Coco; Robert J Omeljaniuk; Vittorio Locatelli · Drug target insights · 2021
Using Synchrotron Radiation Imaging Techniques to Elucidate the Actions of Hexarelin in the Heart of Small Animal Models.
Mark T Waddingham; Hirotsugu Tsuchimochi; Takashi Sonobe; Ryotaro Asano; Huiling Jin; Connie P C Ow; Daryl O Schwenke; Rajesh Katare; Kohki Aoyama; Keiji Umetani; Masato Hoshino; Kentaro Uesugi · Frontiers in physiology · 2021
SARS-CoV-2 RNA Dependent RNA polymerase (RdRp) - A drug repurposing study.
Jamshaid Ahmad; Saima Ikram; Fawad Ahmad; Irshad Ur Rehman; Maryam Mushtaq · Heliyon · 2020
Hexarelin attenuates atherosclerosis via inhibiting LOX-1-NF-κB signaling pathway-mediated macrophage ox-LDL uptake in ApoE-/- mice.
Xiu-Li Cheng; Fan Ding; De-Ping Wang; Lan Zhou; Ji-Min Cao · Peptides · 2019
Hexarelin protects cardiac H9C2 cells from angiotensin II-induced hypertrophy via the regulation of autophagy.
E Agbo; M-X Li; Y-Q Wang; R-O Saahene; J Massaro; G-Z Tian · Die Pharmazie · 2019
Modulation of PTEN by hexarelin attenuates coronary artery ligation-induced heart failure in rats.
Elvis Agbo; Donhai Liu; Meixiu Li; Roland Osei Saahene; Liqiang Chen; Lunpeng Zhao; Yiquan Wang; Guozhong Tian · Turkish journal of medical sciences · 2019
Improvement of cardiomyocyte function by in vivo hexarelin treatment in streptozotocin-induced diabetic rats.
Xinli Zhang; Linbing Qu; Ling Chen; Chen Chen · Physiological reports · 2018
The CD36-PPARγ Pathway in Metabolic Disorders.
Loïze Maréchal; Maximilien Laviolette; Amélie Rodrigue-Way; Baly Sow; Michèle Brochu; Véronique Caron; André Tremblay · International journal of molecular sciences · 2018
The Safety and Efficacy of Growth Hormone Secretagogues.
John T Sigalos; Alexander W Pastuszak · Sexual medicine reviews · 2018
The Growth Hormone Secretagogue Hexarelin Protects Rat Cardiomyocytes From in vivo Ischemia/Reperfusion Injury Through Interleukin-1 Signaling Pathway.
Jiannan Huang; Yi Li; Juan Zhang; Yusheng Liu; Qinghua Lu · International heart journal · 2017
The cardiovascular action of hexarelin.
Yuanjie Mao; Takeshi Tokudome; Ichiro Kishimoto · Journal of geriatric cardiology : JGC · 2014
We are ageing.
Genovefa D Kolovou; Vana Kolovou; Sophie Mavrogeni · BioMed research international · 2014
New active series of growth hormone secretagogues.
Vincent Guerlavais; Damien Boeglin; Delphine Mousseaux; Catherine Oiry; Annie Heitz; Romano Deghenghi; Vittorio Locatelli; Antonio Torsello; Corrado Ghé; Filomena Catapano; Giampiero Muccioli; Jean-Claude Galleyrand · Journal of medicinal chemistry · 2003
Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation.
I Pettersson; G Muccioli; R Granata; R Deghenghi; E Ghigo; C Ohlsson; J Isgaard · The Journal of endocrinology · 2002
Hexarelin protects H9c2 cardiomyocytes from doxorubicin-induced cell death.
N Filigheddu; A Fubini; G Baldanzi; S Cutrupi; C Ghè; F Catapano; F Broglio; A Bosia; M Papotti; G Muccioli; E Ghigo; R Deghenghi · Endocrine · 2001
Hexarelin--evaluation of factors influencing oral bioavailability and ways to improve absorption.
C Westberg; K Benkestock; A Fatouros; M Svensson; B Sjöström · The Journal of pharmacy and pharmacology · 2001
Kinetics and disposition of hexarelin, a peptidic growth hormone secretagogue, in rats.
M Roumi; S Marleau; P du Souich; T Maggi; R Deghenghi; H Ong · Drug metabolism and disposition: the biological fate of chemicals · 2000
Growth hormone in obesity.
M Scacchi; A I Pincelli; F Cavagnini · International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity · 1999
Hexarelin as a test of pituitary reserve in patients with pituitary disease.
M Korbonits; G Kaltsas; L A Perry; A B Grossman; J P Monson; G M Besser; P J Trainer · Clinical endocrinology · 1999
The effect of chronic hexarelin administration on the pituitary-adrenal axis and prolactin.
A Rahim; P A O'Neill; S M Shalet · Clinical endocrinology · 1999
Does desensitization to hexarelin occur?
A Rahim; S M Shalet · Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 1998
Hexarelin-induced growth hormone, cortisol, and prolactin release: a dose-response study.
A F Massoud; P C Hindmarsh; C G Brook · The Journal of clinical endocrinology and metabolism · 1996
Legacy research context
Context from the legacy curated dataset. Its counts describe that dataset and are separate from the live approved source records above.
Researchers represented
- Mosa RM
- Zhang Z
- Shao R
- Deng C
- Chen J
- Chen C
- Mao Y
- Tokudome T
- Kishimoto I
- Kolovou GD
- Kolovou V
- Mavrogeni S
- Ghigo E
- Arvat E
- Muccioli G
- Camanni F