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Published peptide research references

GHK-Cu

Governed registry record

25 approved source records with original-source links. Source verification confirms the reference and its connection to this record; it does not certify every scientific conclusion or establish safety or efficacy.

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Approved source records

  1. Glycyl-L-histidyl-L-lysine-Cu2+ (GHK-Cu) Attenuates CuSO4 or LPS induced-inflammation in Zebrafish larvae model.

    Jing Hu, Chao Zhang, Feifei Wang · 2026

    DOI: 10.1016/j.ejphar.2026.178880PMID: 41997403

  2. PubChem Compound Summary for CID 378611, GHK-Cu

    2026

  3. Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?

    Karolina Ogórek, Kinga Nowak, Emilia Wadych, Lena Ruzik, Andrei R Timerbaev, Magdalena Matczuk · 2025

    DOI: 10.3390/molecules30010136PMID: 39795193

  4. Copper Complexes with New Glycyl-l-histidyl-l-lysine-Hyaluronan Conjugates Show Antioxidant Properties and Osteogenic and Angiogenic Synergistic Effects.

    Valentina Greco, Valeria Lanza, Barbara Tomasello, Irina Naletova, Warren R L Cairns, Sebastiano Sciuto, Enrico Rizzarelli · 2025

    DOI: 10.1021/acs.bioconjchem.4c00545PMID: 40123442

  5. Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective.

    Seyedeh Maryam Mortazavi, Seyyed Ali Mohammadi Vadoud, Hamid Reza Moghimi · 2025

    DOI: 10.34172/bi.30071PMID: 39963574

  6. The glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6.

    Yiding Bian, Mingming Deng, Jia Liu, Jiaye Li, Qin Zhang, Zilin Wang, Liwei Liao, Jinrui Miao · 2024

    DOI: 10.1016/j.redox.2024.103237PMID: 38879894

  7. Glycyl-l-histidyl-l-lysine-Cu2+ rescues cigarette smoking-induced skeletal muscle dysfunction via a sirtuin 1-dependent pathway.

    Mingming Deng, Qin Zhang, Liming Yan, Yiding Bian, Ruixia Li, Jinghan Gao, Yingxi Wang, Jinrui Miao · 2023

    DOI: 10.1002/jcsm.13213PMID: 36905132

  8. Relief of ovalbumin-induced airway remodeling by the glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex via activation of SIRT1 in airway epithelial cells.

    Qin Zhang, Jia Liu, Ming-Ming Deng, Run Tong, Gang Hou · 2023

    DOI: 10.1016/j.biopha.2023.114936PMID: 37257226

  9. Glycyl-L-histidyl-L-lysine-Cu2+ attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway.

    Qin Zhang, Liming Yan, Jingwen Lu, Xiaoming Zhou · 2022

    DOI: 10.3389/fmolb.2022.925700PMID: 35936787

  10. Copper-tripeptides (cuzymes) with peroxidase-mimetic activity.

    Le Truc Nguyen, Wing Fat Ho, Kun-Lin Yang · 2020

    DOI: 10.1039/d0ra02472dPMID: 35515638

  11. The potential of GHK as an anti-aging peptide.

    Yan Dou, Amanda Lee, Lida Zhu, John Morton, Warren Ladiges · 2020

    DOI: 10.31491/apt.2020.03.014PMID: 35083444

  12. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

    2018

    DOI: 10.3390/ijms19071987

  13. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration

    2015

    DOI: 10.1155/2015/648108

  14. The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.

    Loren Pickart, Jessica Michelle Vasquez-Soltero, Anna Margolina · 2012

    DOI: 10.1155/2012/324832PMID: 22666519

  15. The human tri-peptide GHK and tissue remodeling.

    Loren Pickart · 2008

    DOI: 10.1163/156856208784909435PMID: 18644225

  16. ESI-MS study of the mechanism of glycyl-l-histidyl-l-lysine-Cu(II) complex transport through model membrane of stratum corneum.

    Lena Mazurowska, Mirosław Mojski · 2007

    DOI: 10.1016/j.talanta.2006.11.034PMID: 19071668

  17. Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits

    2006

  18. Expression of glycosaminoglycans and small proteoglycans in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(2+).

    A Siméon, Y Wegrowski, Y Bontemps, F X Maquart · 2000

    DOI: 10.1046/j.1523-1747.2000.00166.xPMID: 11121126

  19. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures.

    A Siméon, H Emonard, W Hornebeck, F X Maquart · 2000

    DOI: 10.1016/s0024-3205(00)00803-1PMID: 11045606

  20. Effects of the tripeptide glycyl-L-histidyl-L-lysine copper complex on osteoblastic cell spreading, attachment and phenotype.

    D Godet, P J Marie · 1995

    PMID: 8747089

  21. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds.

    F X Maquart, G Bellon, B Chaqour, J Wegrowski, L M Patt, R E Trachy, J C Monboisse, F Chastang · 1993

    DOI: 10.1172/JCI116842PMID: 8227353

  22. Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+.

    Y Wegrowski, F X Maquart, J P Borel · 1992

    DOI: 10.1016/0024-3205(92)90504-iPMID: 1522753

  23. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+.

    F X Maquart, L Pickart, M Laurent, P Gillery, J C Monboisse, J P Borel · 1988

    DOI: 10.1016/0014-5793(88)80509-xPMID: 3169264

  24. Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells

    1980

    DOI: 10.1038/288715a0

  25. Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver

    1973

    DOI: 10.1038/243085a0