Research across borders

Worldwide Study Finder

Where are peptides being studied? Explore registered human studies by product, phase, condition and location — from early development through Phase 4, alongside studies where phase does not apply.

Searchable results come from ClinicalTrials.gov and include international sites. For broader coverage, use the worldwide and regional registries below. No single registry captures every study.

Find studies Explore world registries Peptide directory

Find a study

Enter a peptide, product, condition or location. Try generic names, brand names and development codes separately. Results are registry search matches, not automatically verified links to a WPF peptide record.

Search terms are sent to ClinicalTrials.gov and appear in the page URL. Do not enter personal or medical identifying information. Registry records are served with up to a one-hour cache; registry updates themselves can lag real-world changes.

Registry search results

Matching records; showing 20 on this page, newest registry updates first. Search checked 2026-11-08 17:46 UTC. Counts are registry matches, not unique peptides or a worldwide total.

Phase 3CompletedINTERVENTIONAL

A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation

ClinicalTrials.gov · NCT02809105 · Registry updated: 2024-10-18

Condition / research focus: Chronic Constipation
Sponsor: Astellas Pharma Inc
Countries with listed sites: Japan
Registry dates and results: Start: 2016-06-24. Completion: 2017-11-10 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

linaclotide (drug) — also listed as: ASP0456
Placebo (drug)

Where the study takes place — 39 listed sites

Site status can differ from overall study status. This list includes all reported sites, even when your search specifies one location. Confirm availability and eligibility with the study team through the original record.

Site JP00029
Aichi, Japan
Site recruitment: Not reported
Site JP00030
Aichi, Japan
Site recruitment: Not reported
Site JP00021
Chiba, Japan
Site recruitment: Not reported
Site JP00022
Chiba, Japan
Site recruitment: Not reported
Site JP00023
Chiba, Japan
Site recruitment: Not reported
Site JP00024
Chiba, Japan
Site recruitment: Not reported
Site JP00040
Fukuoka, Japan
Site recruitment: Not reported
Site JP00001
Hokkaido, Japan
Site recruitment: Not reported
Site JP00002
Hokkaido, Japan
Site recruitment: Not reported
Site JP00037
Hyōgo, Japan
Site recruitment: Not reported
Site JP00038
Hyōgo, Japan
Site recruitment: Not reported
Site JP00039
Hyōgo, Japan
Site recruitment: Not reported
Site JP00017
Kanagawa, Japan
Site recruitment: Not reported
Site JP00018
Kanagawa, Japan
Site recruitment: Not reported
Site JP00019
Kanagawa, Japan
Site recruitment: Not reported
Site JP00020
Kanagawa, Japan
Site recruitment: Not reported
Site JP00031
Osaka, Japan
Site recruitment: Not reported
Site JP00032
Osaka, Japan
Site recruitment: Not reported
Site JP00033
Osaka, Japan
Site recruitment: Not reported
Site JP00034
Osaka, Japan
Site recruitment: Not reported
Site JP00035
Osaka, Japan
Site recruitment: Not reported
Site JP00036
Osaka, Japan
Site recruitment: Not reported
Site JP00025
Saitama, Japan
Site recruitment: Not reported
Site JP00026
Saitama, Japan
Site recruitment: Not reported
Site JP00027
Saitama, Japan
Site recruitment: Not reported
Site JP00028
Saitama, Japan
Site recruitment: Not reported
Site JP00003
Tokyo, Japan
Site recruitment: Not reported
Site JP00004
Tokyo, Japan
Site recruitment: Not reported
Site JP00005
Tokyo, Japan
Site recruitment: Not reported
Site JP00006
Tokyo, Japan
Site recruitment: Not reported
Site JP00007
Tokyo, Japan
Site recruitment: Not reported
Site JP00008
Tokyo, Japan
Site recruitment: Not reported
Site JP00009
Tokyo, Japan
Site recruitment: Not reported
Site JP00010
Tokyo, Japan
Site recruitment: Not reported
Site JP00011
Tokyo, Japan
Site recruitment: Not reported
Site JP00012
Tokyo, Japan
Site recruitment: Not reported
Site JP00013
Tokyo, Japan
Site recruitment: Not reported
Site JP00014
Tokyo, Japan
Site recruitment: Not reported
Site JP00015
Tokyo, Japan
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy

ClinicalTrials.gov · NCT05291325 · Registry updated: 2024-06-20

Condition / research focus: Bowel Preparation for Colonoscopy
Sponsor: Changhai Hospital
Countries with listed sites: China
Registry dates and results: Start: 2022-05-25. Completion: 2024-04-28 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

3L PEG + Linaclotide (drug)
3L PEG (drug)
2L PEG + Linaclotide (drug)

Where the study takes place — 1 listed sites

Changhai Hospital, Naval Medical University
Shanghai, China
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

Application of Linaclotide Capsule in Bowel Preparation for Patients at High Risk of Inadequate Bowel Preparation

ClinicalTrials.gov · NCT05379491 · Registry updated: 2024-05-23

Condition / research focus: Colonoscopy
Sponsor: Zhiguo Liu
Countries with listed sites: China
Registry dates and results: Start: 2022-08-01. Completion: 2023-07-15 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

3 L PEG + linaclotide (drug)
3 L PEG + placebo (drug)

Where the study takes place — 8 listed sites

Ningxia Hui Autonomous Region People's Hospital
Yinchuan, Ningxia, China
Site recruitment: Not reported
Xi'an Central Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Xi'an Jiaotong University Second Affiliated Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Air Force 986 Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Xijing Hospital of Digestive Diseases
Xi'an, Shaanxi, China
Site recruitment: Not reported
Shaanxi Provincial People's Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Linfen Central Hospital
Linfen, Shanxi, China
Site recruitment: Not reported
The Second Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

Evaluate the Safety of Linaclotide in IBS-C Patients in China

ClinicalTrials.gov · NCT04462900 · Registry updated: 2024-05-13

Condition / research focus: Irritable Bowel Syndrome-IBS
Sponsor: AstraZeneca
Countries with listed sites: China
Registry dates and results: Start: 2020-09-18. Completion: 2023-02-03 (may be estimated). No results posted in this registry response.

Products and interventions (0)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Where the study takes place — 29 listed sites

Research Site
Baotou, China
Site recruitment: Not reported
Research Site
Beijing, China
Site recruitment: Not reported
Research Site
Beijing, China
Site recruitment: Not reported
Research Site
Binzhou, China
Site recruitment: Not reported
Research Site
Chengdu, China
Site recruitment: Not reported
Research Site
Chongqing, China
Site recruitment: Not reported
Research Site
Guangzhou, China
Site recruitment: Not reported
Research Site
Guangzhou, China
Site recruitment: Not reported
Research Site
Guangzhou, China
Site recruitment: Not reported
Research Site
Jinan, China
Site recruitment: Not reported
Research Site
Leshan, China
Site recruitment: Not reported
Research Site
Nanchang, China
Site recruitment: Not reported
Research Site
Nanjing, China
Site recruitment: Not reported
Research Site
Nanjing, China
Site recruitment: Not reported
Research Site
Qingdao, China
Site recruitment: Not reported
Research Site
Shanghai, China
Site recruitment: Not reported
Research Site
Shanghai, China
Site recruitment: Not reported
Research Site
Shanghai, China
Site recruitment: Not reported
Research Site
Shenyang, China
Site recruitment: Not reported
Research Site
Shenzhen, China
Site recruitment: Not reported
Research Site
Shenzhen, China
Site recruitment: Not reported
Research Site
Suzhou, China
Site recruitment: Not reported
Research Site
Taiyuan, China
Site recruitment: Not reported
Research Site
Tianjin, China
Site recruitment: Not reported
Research Site
Ürümqi, China
Site recruitment: Not reported
Research Site
Wenzhou, China
Site recruitment: Not reported
Research Site
Wuhan, China
Site recruitment: Not reported
Research Site
Xi'an, China
Site recruitment: Not reported
Research Site
Zhengzhou, China
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

A Comparison of Three Different Treatment Options for Irritable Bowel Syndrome

ClinicalTrials.gov · NCT02970591 · Registry updated: 2022-10-27

Condition / research focus: Irritable Bowel Syndrome
Sponsor: Sahlgrenska University Hospital
Countries with listed sites: Sweden
Registry dates and results: Start: 2017-01. Completion: 2022-04-29 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Traditional dietary advice and low FODMAP content (other)
Low carbohydrate diet (other)
Optimized Medical treatment (other)

Where the study takes place — 1 listed sites

Magnus Simren
Gothenburg, Non-US/Non-Canadian, Sweden
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableTerminatedOBSERVATIONAL

Assessment of Responsiveness to Treatment by Experience Sampling Method

ClinicalTrials.gov · NCT03336034 · Registry updated: 2022-05-25

Condition / research focus: Constipation-predominant Irritable Bowel Syndrome
Sponsor: Maastricht University Medical Center
Countries with listed sites: Netherlands
Registry dates and results: Start: 2018-01-01. Completion: 2022-05-01 (may be estimated). No results posted in this registry response.

Products and interventions (0)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Where the study takes place — 1 listed sites

Maastricht University Medical Center
Maastricht, Netherlands
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

ClinicalTrials.gov · NCT04110145 · Registry updated: 2022-04-26

Condition / research focus: Functional Constipation
Sponsor: Allergan
Countries with listed sites: United States
Registry dates and results: Start: 2019-10-14. Completion: 2021-04-20 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Placebo (drug)

Where the study takes place — 18 listed sites

Central Research Associates, Inc
Birmingham, Alabama, United States
Site recruitment: Not reported
HealthStar Research
Hot Springs, Arkansas, United States
Site recruitment: Not reported
Preferred Clinical Research Partners
Little Rock, Arkansas, United States
Site recruitment: Not reported
Advanced Research Center
Anaheim, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
Center for Clinical Trials, LLC
Paramount, California, United States
Site recruitment: Not reported
Prohealth Research Center
Doral, Florida, United States
Site recruitment: Not reported
South Miami Medical & Research Group, Inc.
Miami, Florida, United States
Site recruitment: Not reported
River Birch Research Alliance, LLC
Blue Ridge, Georgia, United States
Site recruitment: Not reported
SleepCare Research Institute, Inc.
Stockbridge, Georgia, United States
Site recruitment: Not reported
Virgo Carter Pediatrics
Silver Spring, Maryland, United States
Site recruitment: Not reported
Minnesota Gastroenterology PA
Minneapolis, Minnesota, United States
Site recruitment: Not reported
David M. Headley, MD, P.A.
Port Gibson, Mississippi, United States
Site recruitment: Not reported
Foundation Pediatrics Med Clinical Research Partners, LLC
East Orange, New Jersey, United States
Site recruitment: Not reported
Advantage Clinical Trials
The Bronx, New York, United States
Site recruitment: Not reported
Coastal Pediatric Research
Charleston, South Carolina, United States
Site recruitment: Not reported
Coastal Pediatric Research
Mt. Pleasant, South Carolina, United States
Site recruitment: Not reported
Clinical Research Partners, LLC
Richmond, Virginia, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 4UnknownINTERVENTIONAL

Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders

ClinicalTrials.gov · NCT05134584 · Registry updated: 2021-12-13

Condition / research focus: Functional Dyspepsia; Constipation-predominant Irritable Bowel Syndrome
Sponsor: RenJi Hospital
Countries with listed sites: China
Registry dates and results: Start: 2021-01-01. Completion: 2022-02 (may be estimated). No results posted in this registry response.

Products and interventions (4)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug) — also listed as: Linzess
Lactulose (drug) — also listed as: Duphalac
Omeprazol (drug)
Itopride (drug)

Where the study takes place — 1 listed sites

RenJiH
Shanghai, Shanghai Municipality, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 4TerminatedINTERVENTIONAL

A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)

ClinicalTrials.gov · NCT02837783 · Registry updated: 2021-12-06

Condition / research focus: Irritable Bowel Syndrome Characterized by Constipation
Sponsor: Ironwood Pharmaceuticals, Inc.
Countries with listed sites: United Kingdom
Registry dates and results: Start: 2016-12-21. Completion: 2018-10-31 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Peter Whorwell
Wythenshawe, Manchester, United Kingdom
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableUnknownINTERVENTIONAL

Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation

ClinicalTrials.gov · NCT05137145 · Registry updated: 2021-11-30

Condition / research focus: Bowel Preparation
Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University
Countries with listed sites: China
Registry dates and results: Start: 2021-09-01. Completion: 2022-04-30 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Compound Polyethylene Glycol Electrolyte Powder (drug)

Where the study takes place — 1 listed sites

The second affiliated hospital of xi'an jiaotong university
Xi'an, Shaanxi, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Not applicableWithdrawnINTERVENTIONAL

HygiRelief Procedure and HygiSample Evaluation for Functional Constipation

ClinicalTrials.gov · NCT04532879 · Registry updated: 2021-09-17

Condition / research focus: Rome IV Functional Constipation
Sponsor: HyGIeaCare, Inc.
Countries with listed sites: No country reported
Registry dates and results: Start: 2021-09. Completion: 2022-06 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

HygiPrep (HyGIeaCare System) (device) — also listed as: HygiSample (stool collection for microbiome evaluation)

Where the study takes place — 0 listed sites

The registry does not list facilities in this record. This does not mean the study has no sites.

Original record, eligibility, contacts and results →

Phase not reported / not applicableWithdrawnOBSERVATIONAL

Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation

ClinicalTrials.gov · NCT03342287 · Registry updated: 2021-08-31

Condition / research focus: Constipation; Irritable Bowel Syndrome
Sponsor: McMaster University
Countries with listed sites: Canada
Registry dates and results: Start: 2016-03. Completion: 2021-03 (may be estimated). No results posted in this registry response.

Products and interventions (4)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

questionnaires (other)
cognitive evaluation (other)
Blood (other)
Fecal sample (other)

Where the study takes place — 1 listed sites

McMaster University Medical Centre
Hamilton, Ontario, Canada
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 3UnknownINTERVENTIONAL

Evaluation of Clinical Equivalence Between Two Linaclotide Products in the Treatment of Chronic Idiopathic Constipation

ClinicalTrials.gov · NCT04804267 · Registry updated: 2021-03-18

Condition / research focus: Chronic Idiopathic Constipation
Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.
Countries with listed sites: China
Registry dates and results: Start: 2021-03-05. Completion: 2022-08-31 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
LINZESS® (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Renji Hospital, Medical Collge of Shanghai Jiaotong University
Shanghai, Shanghai Municipality, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 2TerminatedINTERVENTIONAL

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation

ClinicalTrials.gov · NCT02559817 · Registry updated: 2020-12-28

Condition / research focus: Irritable Bowel Syndrome With Constipation
Sponsor: Forest Laboratories
Countries with listed sites: Canada · United States
Registry dates and results: Start: 2015-11-01. Completion: 2019-08-30 (may be estimated). Results are posted in this registry.

Products and interventions (5)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide Dose A (drug) — also listed as: Linzess
Linaclotide Dose B (drug) — also listed as: Linzess
Linaclotide Dose C (drug) — also listed as: Linzess
Linaclotide Approved Adult Dose (drug) — also listed as: Linzess
Matching Placebo (drug) — also listed as: Linzess

Where the study takes place — 48 listed sites

HealthStar Research, LLC
Hot Springs, Arkansas, United States
Site recruitment: Not reported
Applied Research Center of Arkansas
Little Rock, Arkansas, United States
Site recruitment: Not reported
Advanced Research Center - Site 069
Anaheim, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
WCCT Global, LLC
Costa Mesa, California, United States
Site recruitment: Not reported
ACTCA, Inc
Los Angeles, California, United States
Site recruitment: Not reported
Children's Hospital Los Angeles
Los Angeles, California, United States
Site recruitment: Not reported
Center for Clinical Trials, LLC
Paramount, California, United States
Site recruitment: Not reported
University of California at San Francisco
San Francisco, California, United States
Site recruitment: Not reported
Advanced Medical Research Center
Miami, Florida, United States
Site recruitment: Not reported
Children's Center for Digestive Health Care LLC
Atlanta, Georgia, United States
Site recruitment: Not reported
Sleepcare Clinical Research Institute
Stockbridge, Georgia, United States
Site recruitment: Not reported
Methodist Medical Center
Peoria, Illinois, United States
Site recruitment: Not reported
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
Willis-Knighton Physician Network
Shreveport, Louisiana, United States
Site recruitment: Not reported
Certified Research Consultants Virgo/Carter Pediatrics
Silver Spring, Maryland, United States
Site recruitment: Not reported
GI Associates and Endoscopy Center
Jackson, Mississippi, United States
Site recruitment: Not reported
Children's Mercy Hospital
Kansas City, Missouri, United States
Site recruitment: Not reported
Boys Town National Research Hospital
Boys Town, Nebraska, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Goryeb Children's Hospital
Morristown, New Jersey, United States
Site recruitment: Not reported
Columbia University Medical Center and Morgan Stanley Children's Hospital of New York
New York, New York, United States
Site recruitment: Not reported
Asheboro Research Associates - Site 022
Asheboro, North Carolina, United States
Site recruitment: Not reported
Capital Pediatrics and Adolescent Center PLLC
Raleigh, North Carolina, United States
Site recruitment: Not reported
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Site recruitment: Not reported
Ohio Pediatric Research Association
Dayton, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
St. Christopher's Hospital for Children
Philadelphia, Pennsylvania, United States
Site recruitment: Not reported
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Preferred Primary Care Physicians, Inc.
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Frontier Clinical Research, LLC
Scottdale, Pennsylvania, United States
Site recruitment: Not reported
Montgomery Medical Inc.
Smithfield, Pennsylvania, United States
Site recruitment: Not reported
Rhode Island Hospital
Providence, Rhode Island, United States
Site recruitment: Not reported
Coastal Pediatric Research
Charleston, South Carolina, United States
Site recruitment: Not reported
Coastal Pediatrics Associates
Mt. Pleasant, South Carolina, United States
Site recruitment: Not reported
Cook Children's Medical Center
Fort Worth, Texas, United States
Site recruitment: Not reported
Texas Children's Hospital/Baylor College Medicine
Houston, Texas, United States
Site recruitment: Not reported
Houston Clinical Research Associates
Houston, Texas, United States
Site recruitment: Not reported
Sun Research Institute
San Antonio, Texas, United States
Site recruitment: Not reported
ClinPoint Trials
Waxahachie, Texas, United States
Site recruitment: Not reported
Children's Hospital of The King's Daughters
Norfolk, Virginia, United States
Site recruitment: Not reported
Virginia Tech Carilion School of Medicine Pediatric Gastroenterology
Roanoke, Virginia, United States
Site recruitment: Not reported
MultiCare Institute for Research and Innovation
Tacoma, Washington, United States
Site recruitment: Not reported
Aurora Health Care, Aurora Medical Center in Summit
Summit, Wisconsin, United States
Site recruitment: Not reported
Children's Hospital of Western Ontario
London, Ontario, Canada
Site recruitment: Not reported
Physician's Clinical Research Inc.
Vaughan, Ontario, Canada
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically

ClinicalTrials.gov · NCT02220348 · Registry updated: 2020-12-19

Condition / research focus: Breast Feeding; Constipation; Irritable Bowel Syndrome
Sponsor: Forest Laboratories
Countries with listed sites: United States
Registry dates and results: Start: 2014-07-31. Completion: 2019-05-31 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

linaclotide (drug) — also listed as: Linzess

Where the study takes place — 2 listed sites

University of Iowa
Iowa City, Iowa, United States
Site recruitment: Not reported
Digestive Disease Specialists Inc (DDSI)
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 3CompletedINTERVENTIONAL

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

ClinicalTrials.gov · NCT03573908 · Registry updated: 2020-12-01

Condition / research focus: Irritable Bowel Syndrome Characterized by Constipation
Sponsor: Ironwood Pharmaceuticals, Inc.
Countries with listed sites: United States
Registry dates and results: Start: 2018-06-20. Completion: 2019-04-10 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug) — also listed as: Linzess
Placebo (drug)

Where the study takes place — 79 listed sites

Clinical Research Associates
Huntsville, Alabama, United States
Site recruitment: Not reported
Elite Clinical Studies
Phoenix, Arizona, United States
Site recruitment: Not reported
Adobe Clinical Research, LLC
Tucson, Arizona, United States
Site recruitment: Not reported
Arkansas Gastroenterology
North Little Rock, Arkansas, United States
Site recruitment: Not reported
GW Research, Inc.
Chula Vista, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
Diagnamics, Inc.
Encinitas, California, United States
Site recruitment: Not reported
MD Studies, Inc.
Fountain Valley, California, United States
Site recruitment: Not reported
Paragon Rx Clinical, Inc. - Garden Grove
Garden Grove, California, United States
Site recruitment: Not reported
Grossmont Center For Clinical Research
La Mesa, California, United States
Site recruitment: Not reported
Facey Medical Foundation
Mission Hills, California, United States
Site recruitment: Not reported
Providence Clinical Research
North Hollywood, California, United States
Site recruitment: Not reported
Precision Research Institute
San Diego, California, United States
Site recruitment: Not reported
Paragon Rx Clinical, Inc.- Santa Ana
Santa Ana, California, United States
Site recruitment: Not reported
Millennium Clinical Trials
Thousand Oaks, California, United States
Site recruitment: Not reported
St. Joseph Heritage Healthcare
Yorba Linda, California, United States
Site recruitment: Not reported
Connecticut Clinical Research Institute
Bristol, Connecticut, United States
Site recruitment: Not reported
Chase Medical Research, LLC
Waterbury, Connecticut, United States
Site recruitment: Not reported
Clinical Research of South Florida
Coral Gables, Florida, United States
Site recruitment: Not reported
Avail Clinical Research, LLC
DeLand, Florida, United States
Site recruitment: Not reported
Palmetto Research, LLC
Hialeah, Florida, United States
Site recruitment: Not reported
Nature Coast Clinical Research, LLC
Inverness, Florida, United States
Site recruitment: Not reported
The Chappel Group Research
Kissimmee, Florida, United States
Site recruitment: Not reported
Jesscan Medical Research
Miami, Florida, United States
Site recruitment: Not reported
Well Pharma Medical Research Corporation
Miami, Florida, United States
Site recruitment: Not reported
New Horizon Research Center
Miami, Florida, United States
Site recruitment: Not reported
San Marcus Research Clinic, Inc.
Miami Lakes, Florida, United States
Site recruitment: Not reported
Ocean Blue Medical Research Center, Inc.
Miami Springs, Florida, United States
Site recruitment: Not reported
Ormond Medical Arts Pharmaceutical Research Center
Ormond Beach, Florida, United States
Site recruitment: Not reported
Precision Clinical Research
Sunrise, Florida, United States
Site recruitment: Not reported
Meridien Research - Tampa
Tampa, Florida, United States
Site recruitment: Not reported
Palm Beach Research Center
West Palm Beach, Florida, United States
Site recruitment: Not reported
Research Institute of Central Florida, LLC
Winter Park, Florida, United States
Site recruitment: Not reported
Mount Vernon Clinical Research, LLC
Sandy Springs, Georgia, United States
Site recruitment: Not reported
Clinical Trials Management, LLC
Metairie, Louisiana, United States
Site recruitment: Not reported
Delta Research Partners, LLC
Monroe, Louisiana, United States
Site recruitment: Not reported
Louisiana Research Center, LLC
Shreveport, Louisiana, United States
Site recruitment: Not reported
Alan A. Rosen, MD, PA
Baltimore, Maryland, United States
Site recruitment: Not reported
Meritus Center For Clinical Research
Hagerstown, Maryland, United States
Site recruitment: Not reported
Boston Clinical Trials, Inc.
Boston, Massachusetts, United States
Site recruitment: Not reported
MedVadis Research Corporation
Watertown, Massachusetts, United States
Site recruitment: Not reported
Gastroenterology Associates of West Michigan
Wyoming, Michigan, United States
Site recruitment: Not reported
Gastrointestinal Associates PA
Flowood, Mississippi, United States
Site recruitment: Not reported
St. Louis Center For Clinical Research
St Louis, Missouri, United States
Site recruitment: Not reported
Bozeman Health Deaconess Hospital
Bozeman, Montana, United States
Site recruitment: Not reported
Clinical Research of South Nevada
Las Vegas, Nevada, United States
Site recruitment: Not reported
Healthwise Medical Associates
Brooklyn, New York, United States
Site recruitment: Not reported
Long Island Gastrointestinal Research Group, LLP
Great Neck, New York, United States
Site recruitment: Not reported
Carolina Digestive Health Associates
Charlotte, North Carolina, United States
Site recruitment: Not reported
Carolina Digestive Health Associates
Concord, North Carolina, United States
Site recruitment: Not reported
Cumberland Research Associates
Fayetteville, North Carolina, United States
Site recruitment: Not reported
Peters Medical Research, LLC
High Point, North Carolina, United States
Site recruitment: Not reported
Wake Research Associates, LLC
Raleigh, North Carolina, United States
Site recruitment: Not reported
PMG Research of Wilmington
Wilmington, North Carolina, United States
Site recruitment: Not reported
Clinical Trials of America - North Carolina, LLC
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
Lyndhurst Clinical Research
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
PMG Research of Winston-Salem
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
Lillestol Research
Fargo, North Dakota, United States
Site recruitment: Not reported
Hightop Medical Research Center
Cincinnati, Ohio, United States
Site recruitment: Not reported
New Horizons Clinical Research
Cincinnati, Ohio, United States
Site recruitment: Not reported
Remington Davis, Inc.
Columbus, Ohio, United States
Site recruitment: Not reported
Dayton Gastroenterology, Inc.
Dayton, Ohio, United States
Site recruitment: Not reported
Hometown Urgent Care and Research
Dayton, Ohio, United States
Site recruitment: Not reported
Great Lakes Gastroenterology Research, LLC
Mentor, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
Partners In Clinical Research
Cumberland, Rhode Island, United States
Site recruitment: Not reported
Mountain View Clinical Research, Inc.
Greer, South Carolina, United States
Site recruitment: Not reported
Meridian Clinical Research
Dakota Dunes, South Dakota, United States
Site recruitment: Not reported
ClinSearch, LLC
Chattanooga, Tennessee, United States
Site recruitment: Not reported
New Phase Research & Development
Knoxville, Tennessee, United States
Site recruitment: Not reported
MW Clinical Research Center
Beaumont, Texas, United States
Site recruitment: Not reported
Southwest Clinical Trials
Houston, Texas, United States
Site recruitment: Not reported
Southwest Clinical Trials
Houston, Texas, United States
Site recruitment: Not reported
Quality Research, Inc.
San Antonio, Texas, United States
Site recruitment: Not reported
Diagnostics Research Group
San Antonio, Texas, United States
Site recruitment: Not reported
Stone Oak, LLC dba Discovery Clinical Trials
San Antonio, Texas, United States
Site recruitment: Not reported
Advanced Research Institute
Ogden, Utah, United States
Site recruitment: Not reported
New River Valley Research Institute
Christiansburg, Virginia, United States
Site recruitment: Not reported
Blue Ridge Medical Research
Lynchburg, Virginia, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

ClinicalTrials.gov · NCT02559206 · Registry updated: 2020-04-24

Condition / research focus: Irritable Bowel Syndrome With Constipation
Sponsor: Ironwood Pharmaceuticals, Inc.
Countries with listed sites: United States
Registry dates and results: Start: 2015-10-22. Completion: 2016-09-30 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Matching Placebo (drug)

Where the study takes place — 71 listed sites

Ironwood Investigational Site
Huntsville, Alabama, United States
Site recruitment: Not reported
Ironwood Investigational Site
Phoenix, Arizona, United States
Site recruitment: Not reported
Ironwood Investigational Site
Tucson, Arizona, United States
Site recruitment: Not reported
Ironwood Investigational Site
North Little Rock, Arkansas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Anaheim, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chula Vista, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Garden Grove, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
La Mesa, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Newport Beach, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Orange, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Diego, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Thousand Oaks, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Colorado Springs, Colorado, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bristol, Connecticut, United States
Site recruitment: Not reported
Ironwood Investigational Site
Waterbury, Connecticut, United States
Site recruitment: Not reported
Ironwood Investigational Site
Hialeah, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Kissimmee, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Orlando, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
South Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Tampa, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
West Palm Beach, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Atlanta, Georgia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Oakwood, Georgia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Sandy Springs, Georgia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Evansville, Indiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bastrop, Louisiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Metairie, Louisiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Shreveport, Louisiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Baltimore, Maryland, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chevy Chase, Maryland, United States
Site recruitment: Not reported
Ironwood Investigational Site
Boston, Massachusetts, United States
Site recruitment: Not reported
Ironwood Investigational Site
Watertown, Massachusetts, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chesterfield, Michigan, United States
Site recruitment: Not reported
Ironwood Investigational Site
Wyoming, Michigan, United States
Site recruitment: Not reported
Ironwood Investigational Site
Jackson, Mississippi, United States
Site recruitment: Not reported
Ironwood Investigational Site
St Louis, Missouri, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bozeman, Montana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Las Vegas, Nevada, United States
Site recruitment: Not reported
Ironwood Investigational Site
Las Vegas, Nevada, United States
Site recruitment: Not reported
Ironwood Investigational Site
Brooklyn, New York, United States
Site recruitment: Not reported
Ironwood Investigational Site
Charlotte, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Concord, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Davidson, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Fayetteville, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Wilmington, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Cincinnati, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Cincinnati, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Mentor, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Xenia, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Ironwood Investigational Site
Dakota Dunes, South Dakota, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bristol, Tennessee, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chattanooga, Tennessee, United States
Site recruitment: Not reported
Ironwood Investigational Site
Knoxville, Tennessee, United States
Site recruitment: Not reported
Ironwood Investigational Site
Arlington, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Beaumont, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
El Paso, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Houston, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Antonio, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Antonio, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Antonio, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Ogden, Utah, United States
Site recruitment: Not reported
Ironwood Investigational Site
Sandy City, Utah, United States
Site recruitment: Not reported
Ironwood Investigational Site
Christiansburg, Virginia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Lynchburg, Virginia, United States
Site recruitment: Not reported
Ironwood Investigational Site
La Crosse, Wisconsin, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 4CompletedINTERVENTIONAL

An Open-Label, Long-term Study to Assess the Immunogenicity of LINZESS® (Linaclotide) Administered Orally to Adult Participants With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation

ClinicalTrials.gov · NCT02590432 · Registry updated: 2019-08-22

Condition / research focus: Irritable Bowel Syndrome With Constipation; Chronic Idiopathic Constipation
Sponsor: Forest Laboratories
Countries with listed sites: United States
Registry dates and results: Start: 2015-11-01. Completion: 2018-02-05 (may be estimated). Results are posted in this registry.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug) — also listed as: LINZESS®

Where the study takes place — 79 listed sites

Pinnacle Research Group, LLC
Anniston, Alabama, United States
Site recruitment: Not reported
North Alabama Research Center, LLC
Athens, Alabama, United States
Site recruitment: Not reported
Alliance Clinical Research
Childersburg, Alabama, United States
Site recruitment: Not reported
G & L Research, LLC
Foley, Alabama, United States
Site recruitment: Not reported
Radiant Research, Inc.
Chandler, Arizona, United States
Site recruitment: Not reported
Radiant Research, Inc.
Scottsdale, Arizona, United States
Site recruitment: Not reported
Clinical Research Institute of Arizona, LLC
Surprise, Arizona, United States
Site recruitment: Not reported
Clinical Research Consortium
Tempe, Arizona, United States
Site recruitment: Not reported
Desert Sun Clinical Research, LLC.
Tucson, Arizona, United States
Site recruitment: Not reported
Preferred Research Partners, Inc.
Little Rock, Arkansas, United States
Site recruitment: Not reported
Applied Research Center of Arkansas
Little Rock, Arkansas, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
Global Clinical Trials LLC
Costa Mesa, California, United States
Site recruitment: Not reported
Diagnamics Inc
Encinitas, California, United States
Site recruitment: Not reported
MD Studies, Inc.
Fountain Valley, California, United States
Site recruitment: Not reported
Research Center of Fresno, Inc.
Fresno, California, United States
Site recruitment: Not reported
VVCRD Clinical Research
Garden Grove, California, United States
Site recruitment: Not reported
Facey Medical Foundation
Mission Hills, California, United States
Site recruitment: Not reported
Clinical Trials Research
Sacramento, California, United States
Site recruitment: Not reported
Northern California Research
Sacramento, California, United States
Site recruitment: Not reported
Artemis Institute for Clinical Research
San Diego, California, United States
Site recruitment: Not reported
Precision Research Institute
San Diego, California, United States
Site recruitment: Not reported
Empire Clinical Research
Upland, California, United States
Site recruitment: Not reported
Lynn Institute of Denver
Denver, Colorado, United States
Site recruitment: Not reported
ZASA Clinical Research
Boynton Beach, Florida, United States
Site recruitment: Not reported
Meridien Research
Bradenton, Florida, United States
Site recruitment: Not reported
Clinical Research of Brandon LLC
Brandon, Florida, United States
Site recruitment: Not reported
Clinical Physiology Associates
Fort Myers, Florida, United States
Site recruitment: Not reported
Direct Helpers Research Center
Hialeah, Florida, United States
Site recruitment: Not reported
Eastern Research, Inc.
Hialeah, Florida, United States
Site recruitment: Not reported
Center for Advanced Gastroenterology
Maitland, Florida, United States
Site recruitment: Not reported
Florida Medical Center and Research, Inc.
Miami, Florida, United States
Site recruitment: Not reported
Clinical Neuroscience Solutions, Inc
Orlando, Florida, United States
Site recruitment: Not reported
Accord Clinical Research
Port Orange, Florida, United States
Site recruitment: Not reported
Meridien Research
St. Petersburg, Florida, United States
Site recruitment: Not reported
River Birch Research Alliance, LLC
Blue Ridge, Georgia, United States
Site recruitment: Not reported
North Georgia Clinical Research
Woodstock, Georgia, United States
Site recruitment: Not reported
Northwest Clinical Trials
Boise, Idaho, United States
Site recruitment: Not reported
Rockford Gastroenterology Associates
Rockford, Illinois, United States
Site recruitment: Not reported
Iowa Digestive Center, PC
Clive, Iowa, United States
Site recruitment: Not reported
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Site recruitment: Not reported
Integrated Clinical Trial Services, Inc.
West Des Moines, Iowa, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Newton, Kansas, United States
Site recruitment: Not reported
Health Science Research Center
Pratt, Kansas, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
KAMP Medical Research Inc
Natchitoches, Louisiana, United States
Site recruitment: Not reported
Coastal Research Associates, Inc.
South Weymouth, Massachusetts, United States
Site recruitment: Not reported
Bay State Clinical Trials, Inc.
Watertown, Massachusetts, United States
Site recruitment: Not reported
Aa Mrc Llc
Flint, Michigan, United States
Site recruitment: Not reported
Beyer Research
Kalamazoo, Michigan, United States
Site recruitment: Not reported
The Center for Clinical Trials, Inc.
Biloxi, Mississippi, United States
Site recruitment: Not reported
Sundance Clinical Research, LLC
St Louis, Missouri, United States
Site recruitment: Not reported
Digestive Health Associates
Reno, Nevada, United States
Site recruitment: Not reported
Albuquerque Clinical Trials
Albuquerque, New Mexico, United States
Site recruitment: Not reported
Lovelace Scientific Resources, Inc.
Albuquerque, New Mexico, United States
Site recruitment: Not reported
Drug Trials America
Hartsdale, New York, United States
Site recruitment: Not reported
Manhattan Medical Research Practice PLLC
New York, New York, United States
Site recruitment: Not reported
DiGiovanna Institute for Medical Education & Research
North Massapequa, New York, United States
Site recruitment: Not reported
UNC Health Care, University of North Carolina Medical Center, Memorial Hospital
Chapel Hill, North Carolina, United States
Site recruitment: Not reported
PharmQuest
Greensboro, North Carolina, United States
Site recruitment: Not reported
Northstate Clinical Research
Lenoir, North Carolina, United States
Site recruitment: Not reported
Digestive Health Specialists, PA
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
New Horizons Clinical Research
Cincinnati, Ohio, United States
Site recruitment: Not reported
Clinical Inquest Center LTD
Dayton, Ohio, United States
Site recruitment: Not reported
Dayton Gastroenterology, Inc.
Dayton, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
The Clinical Trial Center, LLC
Jenkintown, Pennsylvania, United States
Site recruitment: Not reported
Temple University
Philadelphia, Pennsylvania, United States
Site recruitment: Not reported
Preferred Primary Care Physicians, INC
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Montgomery Medical, Inc.
Smithfield, Pennsylvania, United States
Site recruitment: Not reported
Partners In Clinical Research
Cumberland, Rhode Island, United States
Site recruitment: Not reported
Greenville Pharmaceutical Research, Inc.
Greenville, South Carolina, United States
Site recruitment: Not reported
Radiant Research, Inc.
Greer, South Carolina, United States
Site recruitment: Not reported
Clinical Neuroscience Solutions, Inc.
Memphis, Tennessee, United States
Site recruitment: Not reported
Houston Endoscopy & Research Center
Houston, Texas, United States
Site recruitment: Not reported
Research Across America
Plano, Texas, United States
Site recruitment: Not reported
Sun Research Institute
San Antonio, Texas, United States
Site recruitment: Not reported
Charlottesville Medical Research Center, LLC
Charlottesville, Virginia, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableTerminatedINTERVENTIONAL

Efficacy of Linaclotide to Senna for CIC

ClinicalTrials.gov · NCT02239510 · Registry updated: 2019-07-02

Condition / research focus: Chronic Idiopathic Constipation
Sponsor: TriHealth Inc.
Countries with listed sites: United States
Registry dates and results: Start: 2014-09. Completion: 2016-06 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Senna (drug) — also listed as: sennoside
Linzess (drug) — also listed as: Linaclotide

Where the study takes place — 1 listed sites

TriHealth
Cincinnati, Ohio, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

ClinicalTrials.gov · NCT02559570 · Registry updated: 2019-06-19

Condition / research focus: Functional Constipation in Children Ages 6-17 Years
Sponsor: Forest Laboratories
Countries with listed sites: Canada · United States
Registry dates and results: Start: 2015-11-03. Completion: 2018-05-29 (may be estimated). Results are posted in this registry.

Products and interventions (5)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Placebo (drug)
LIN Dose A (drug) — also listed as: LINZESS
LIN Dose B (drug) — also listed as: LINZESS
LIN Dose C (drug) — also listed as: LINZESS
LIN 145 µg (drug) — also listed as: LINZESS

Where the study takes place — 62 listed sites

HealthStar Research, LLC
Hot Springs, Arkansas, United States
Site recruitment: Not reported
Applied Research Center of Arkansas
Little Rock, Arkansas, United States
Site recruitment: Not reported
Advanced Research Center
Anaheim, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
WCCT Global, LLC
Costa Mesa, California, United States
Site recruitment: Not reported
Ark Clinical Research
Long Beach, California, United States
Site recruitment: Not reported
ACTCA, Inc
Los Angeles, California, United States
Site recruitment: Not reported
Children's Hospital Los Angeles
Los Angeles, California, United States
Site recruitment: Not reported
Orange County Research Institute
Ontario, California, United States
Site recruitment: Not reported
Center for Clinical Trials, LLC
Paramount, California, United States
Site recruitment: Not reported
UCSD Rady Children's Hospital
San Diego, California, United States
Site recruitment: Not reported
University of California at San Francisco
San Francisco, California, United States
Site recruitment: Not reported
Ventura Clinical Trials
Ventura, California, United States
Site recruitment: Not reported
Colorado Springs Health Partners, HCP-Clinical Research, LLC
Colorado Springs, Colorado, United States
Site recruitment: Not reported
Nova Southeastern University
Fort Lauderdale, Florida, United States
Site recruitment: Not reported
Homestead Research Institute
Homestead, Florida, United States
Site recruitment: Not reported
RM Medical Research
Homestead, Florida, United States
Site recruitment: Not reported
Advanced Medical Research Center
Miami, Florida, United States
Site recruitment: Not reported
SCORE Physician Alliance, LLC
St. Petersburg, Florida, United States
Site recruitment: Not reported
Children's Center for Digestive Health Care LLC
Atlanta, Georgia, United States
Site recruitment: Not reported
Sleepcare Clinical Research Institute
Stockbridge, Georgia, United States
Site recruitment: Not reported
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
Kentucky Pediatric/ Adult Research
Bardstown, Kentucky, United States
Site recruitment: Not reported
Kosair Children's Hospital - Pediatric Clinical Research Unit
Louisville, Kentucky, United States
Site recruitment: Not reported
Michael W. Simon, MD, PSC
Nicholasville, Kentucky, United States
Site recruitment: Not reported
Willis-Knighton Physician Network
Shreveport, Louisiana, United States
Site recruitment: Not reported
University of Maryland Children's Hospital
Baltimore, Maryland, United States
Site recruitment: Not reported
Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported
University Of Minnesota
Minneapolis, Minnesota, United States
Site recruitment: Not reported
GI Associates and Endoscopy Center
Jackson, Mississippi, United States
Site recruitment: Not reported
Craig A. Speigel, MD
Bridgeton, Missouri, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Goryeb Children's Hospital
Morristown, New Jersey, United States
Site recruitment: Not reported
Columbia University Medical Center and Morgan Stanley
New York, New York, United States
Site recruitment: Not reported
Asheboro Research Associates
Asheboro, North Carolina, United States
Site recruitment: Not reported
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Site recruitment: Not reported
Capital Pediatrics and Adolescent Center PLLC
Raleigh, North Carolina, United States
Site recruitment: Not reported
Ohio Pediatric Research Association
Dayton, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
Pediatric Care Specialists
Johnstown, Pennsylvania, United States
Site recruitment: Not reported
St. Christopher's Hospital for Children
Philadelphia, Pennsylvania, United States
Site recruitment: Not reported
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Preferred Primary Care Physicians, Inc.
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Frontier Clinical Research, LLC
Scottdale, Pennsylvania, United States
Site recruitment: Not reported
Montgomery Medical Inc.
Smithfield, Pennsylvania, United States
Site recruitment: Not reported
Rhode Island Hospital
Providence, Rhode Island, United States
Site recruitment: Not reported
Coastal Pediatric Research
Charleston, South Carolina, United States
Site recruitment: Not reported
Coastal Pediatrics Associates
Mt. Pleasant, South Carolina, United States
Site recruitment: Not reported
Cook Children's Medical Center
Fort Worth, Texas, United States
Site recruitment: Not reported
Texas Children's Hospital/Baylor College Medicine
Houston, Texas, United States
Site recruitment: Not reported
Houston Clinical Research Associates
Houston, Texas, United States
Site recruitment: Not reported
Sun Research Institute
San Antonio, Texas, United States
Site recruitment: Not reported
Southwest Children's Research Associates, P.A.
San Antonio, Texas, United States
Site recruitment: Not reported
ClinPoint Trials
Waxahachie, Texas, United States
Site recruitment: Not reported
Foothill Family Clinic South / J. Lewis Research, Inc.
Salt Lake City, Utah, United States
Site recruitment: Not reported
Pediatric Specialists of Virginia
Fairfax, Virginia, United States
Site recruitment: Not reported
Virginia Tech Carilion School of Medicine Pediatric
Roanoke, Virginia, United States
Site recruitment: Not reported
Seattle Children's Hospital
Seattle, Washington, United States
Site recruitment: Not reported
Stollery Children's Hospital
Edmonton, Alberta, Canada
Site recruitment: Not reported
Children's Hospital of Western Ontario
London, Ontario, Canada
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Explore the world’s study registries

These links open external registries; their records are not merged into the results above. WHO ICTRP provides a broader search across contributing registries. Search the same generic name, aliases and development codes in relevant regions. One multinational study may appear in more than one registry, so compare registration identifiers before counting it twice.

Worldwide

Africa

Pan African Clinical Trial Registry ↗

Americas

Asia

Middle East

Europe

Oceania

Australia / New Zealand — ANZCTR ↗

Registry directory checked October 5, 2026 against the WHO registry network. This is a starting point, not complete coverage of every country or continent. Record availability, language and update schedules vary by registry.

Worldwide Study Finder

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Worldwide Study Finder

Where are peptides being studied? Explore registered human studies by product, phase, condition and location — from early development through Phase 4, alongside studies where phase does not apply.

Searchable results come from ClinicalTrials.gov and include international sites. For broader coverage, use the worldwide and regional registries below. No single registry captures every study.

Find a study

Registry search results

Matching records; showing 20 on this page, newest registry updates first. Search checked 2026-11-08 17:46 UTC. Counts are registry matches, not unique peptides or a worldwide total.

Phase 3CompletedINTERVENTIONAL

A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation

ClinicalTrials.gov · NCT02809105 · Registry updated: 2024-10-18

Condition / research focus: Chronic Constipation
Sponsor: Astellas Pharma Inc
Countries with listed sites: Japan
Registry dates and results: Start: 2016-06-24. Completion: 2017-11-10 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

linaclotide (drug) — also listed as: ASP0456
Placebo (drug)

Where the study takes place — 39 listed sites

Site JP00029
Aichi, Japan
Site recruitment: Not reported
Site JP00030
Aichi, Japan
Site recruitment: Not reported
Site JP00021
Chiba, Japan
Site recruitment: Not reported
Site JP00022
Chiba, Japan
Site recruitment: Not reported
Site JP00023
Chiba, Japan
Site recruitment: Not reported
Site JP00024
Chiba, Japan
Site recruitment: Not reported
Site JP00040
Fukuoka, Japan
Site recruitment: Not reported
Site JP00001
Hokkaido, Japan
Site recruitment: Not reported
Site JP00002
Hokkaido, Japan
Site recruitment: Not reported
Site JP00037
Hyōgo, Japan
Site recruitment: Not reported
Site JP00038
Hyōgo, Japan
Site recruitment: Not reported
Site JP00039
Hyōgo, Japan
Site recruitment: Not reported
Site JP00017
Kanagawa, Japan
Site recruitment: Not reported
Site JP00018
Kanagawa, Japan
Site recruitment: Not reported
Site JP00019
Kanagawa, Japan
Site recruitment: Not reported
Site JP00020
Kanagawa, Japan
Site recruitment: Not reported
Site JP00031
Osaka, Japan
Site recruitment: Not reported
Site JP00032
Osaka, Japan
Site recruitment: Not reported
Site JP00033
Osaka, Japan
Site recruitment: Not reported
Site JP00034
Osaka, Japan
Site recruitment: Not reported
Site JP00035
Osaka, Japan
Site recruitment: Not reported
Site JP00036
Osaka, Japan
Site recruitment: Not reported
Site JP00025
Saitama, Japan
Site recruitment: Not reported
Site JP00026
Saitama, Japan
Site recruitment: Not reported
Site JP00027
Saitama, Japan
Site recruitment: Not reported
Site JP00028
Saitama, Japan
Site recruitment: Not reported
Site JP00003
Tokyo, Japan
Site recruitment: Not reported
Site JP00004
Tokyo, Japan
Site recruitment: Not reported
Site JP00005
Tokyo, Japan
Site recruitment: Not reported
Site JP00006
Tokyo, Japan
Site recruitment: Not reported
Site JP00007
Tokyo, Japan
Site recruitment: Not reported
Site JP00008
Tokyo, Japan
Site recruitment: Not reported
Site JP00009
Tokyo, Japan
Site recruitment: Not reported
Site JP00010
Tokyo, Japan
Site recruitment: Not reported
Site JP00011
Tokyo, Japan
Site recruitment: Not reported
Site JP00012
Tokyo, Japan
Site recruitment: Not reported
Site JP00013
Tokyo, Japan
Site recruitment: Not reported
Site JP00014
Tokyo, Japan
Site recruitment: Not reported
Site JP00015
Tokyo, Japan
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy

ClinicalTrials.gov · NCT05291325 · Registry updated: 2024-06-20

Condition / research focus: Bowel Preparation for Colonoscopy
Sponsor: Changhai Hospital
Countries with listed sites: China
Registry dates and results: Start: 2022-05-25. Completion: 2024-04-28 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

3L PEG + Linaclotide (drug)
3L PEG (drug)
2L PEG + Linaclotide (drug)

Where the study takes place — 1 listed sites

Changhai Hospital, Naval Medical University
Shanghai, China
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

Application of Linaclotide Capsule in Bowel Preparation for Patients at High Risk of Inadequate Bowel Preparation

ClinicalTrials.gov · NCT05379491 · Registry updated: 2024-05-23

Condition / research focus: Colonoscopy
Sponsor: Zhiguo Liu
Countries with listed sites: China
Registry dates and results: Start: 2022-08-01. Completion: 2023-07-15 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

3 L PEG + linaclotide (drug)
3 L PEG + placebo (drug)

Where the study takes place — 8 listed sites

Ningxia Hui Autonomous Region People's Hospital
Yinchuan, Ningxia, China
Site recruitment: Not reported
Xi'an Central Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Xi'an Jiaotong University Second Affiliated Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Air Force 986 Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Xijing Hospital of Digestive Diseases
Xi'an, Shaanxi, China
Site recruitment: Not reported
Shaanxi Provincial People's Hospital
Xi'an, Shaanxi, China
Site recruitment: Not reported
Linfen Central Hospital
Linfen, Shanxi, China
Site recruitment: Not reported
The Second Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

Evaluate the Safety of Linaclotide in IBS-C Patients in China

ClinicalTrials.gov · NCT04462900 · Registry updated: 2024-05-13

Condition / research focus: Irritable Bowel Syndrome-IBS
Sponsor: AstraZeneca
Countries with listed sites: China
Registry dates and results: Start: 2020-09-18. Completion: 2023-02-03 (may be estimated). No results posted in this registry response.

Products and interventions (0)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Where the study takes place — 29 listed sites

Research Site
Baotou, China
Site recruitment: Not reported
Research Site
Beijing, China
Site recruitment: Not reported
Research Site
Beijing, China
Site recruitment: Not reported
Research Site
Binzhou, China
Site recruitment: Not reported
Research Site
Chengdu, China
Site recruitment: Not reported
Research Site
Chongqing, China
Site recruitment: Not reported
Research Site
Guangzhou, China
Site recruitment: Not reported
Research Site
Guangzhou, China
Site recruitment: Not reported
Research Site
Guangzhou, China
Site recruitment: Not reported
Research Site
Jinan, China
Site recruitment: Not reported
Research Site
Leshan, China
Site recruitment: Not reported
Research Site
Nanchang, China
Site recruitment: Not reported
Research Site
Nanjing, China
Site recruitment: Not reported
Research Site
Nanjing, China
Site recruitment: Not reported
Research Site
Qingdao, China
Site recruitment: Not reported
Research Site
Shanghai, China
Site recruitment: Not reported
Research Site
Shanghai, China
Site recruitment: Not reported
Research Site
Shanghai, China
Site recruitment: Not reported
Research Site
Shenyang, China
Site recruitment: Not reported
Research Site
Shenzhen, China
Site recruitment: Not reported
Research Site
Shenzhen, China
Site recruitment: Not reported
Research Site
Suzhou, China
Site recruitment: Not reported
Research Site
Taiyuan, China
Site recruitment: Not reported
Research Site
Tianjin, China
Site recruitment: Not reported
Research Site
Ürümqi, China
Site recruitment: Not reported
Research Site
Wenzhou, China
Site recruitment: Not reported
Research Site
Wuhan, China
Site recruitment: Not reported
Research Site
Xi'an, China
Site recruitment: Not reported
Research Site
Zhengzhou, China
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

A Comparison of Three Different Treatment Options for Irritable Bowel Syndrome

ClinicalTrials.gov · NCT02970591 · Registry updated: 2022-10-27

Condition / research focus: Irritable Bowel Syndrome
Sponsor: Sahlgrenska University Hospital
Countries with listed sites: Sweden
Registry dates and results: Start: 2017-01. Completion: 2022-04-29 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Traditional dietary advice and low FODMAP content (other)
Low carbohydrate diet (other)
Optimized Medical treatment (other)

Where the study takes place — 1 listed sites

Magnus Simren
Gothenburg, Non-US/Non-Canadian, Sweden
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableTerminatedOBSERVATIONAL

Assessment of Responsiveness to Treatment by Experience Sampling Method

ClinicalTrials.gov · NCT03336034 · Registry updated: 2022-05-25

Condition / research focus: Constipation-predominant Irritable Bowel Syndrome
Sponsor: Maastricht University Medical Center
Countries with listed sites: Netherlands
Registry dates and results: Start: 2018-01-01. Completion: 2022-05-01 (may be estimated). No results posted in this registry response.

Products and interventions (0)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Where the study takes place — 1 listed sites

Maastricht University Medical Center
Maastricht, Netherlands
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

ClinicalTrials.gov · NCT04110145 · Registry updated: 2022-04-26

Condition / research focus: Functional Constipation
Sponsor: Allergan
Countries with listed sites: United States
Registry dates and results: Start: 2019-10-14. Completion: 2021-04-20 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Placebo (drug)

Where the study takes place — 18 listed sites

Central Research Associates, Inc
Birmingham, Alabama, United States
Site recruitment: Not reported
HealthStar Research
Hot Springs, Arkansas, United States
Site recruitment: Not reported
Preferred Clinical Research Partners
Little Rock, Arkansas, United States
Site recruitment: Not reported
Advanced Research Center
Anaheim, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
Center for Clinical Trials, LLC
Paramount, California, United States
Site recruitment: Not reported
Prohealth Research Center
Doral, Florida, United States
Site recruitment: Not reported
South Miami Medical & Research Group, Inc.
Miami, Florida, United States
Site recruitment: Not reported
River Birch Research Alliance, LLC
Blue Ridge, Georgia, United States
Site recruitment: Not reported
SleepCare Research Institute, Inc.
Stockbridge, Georgia, United States
Site recruitment: Not reported
Virgo Carter Pediatrics
Silver Spring, Maryland, United States
Site recruitment: Not reported
Minnesota Gastroenterology PA
Minneapolis, Minnesota, United States
Site recruitment: Not reported
David M. Headley, MD, P.A.
Port Gibson, Mississippi, United States
Site recruitment: Not reported
Foundation Pediatrics Med Clinical Research Partners, LLC
East Orange, New Jersey, United States
Site recruitment: Not reported
Advantage Clinical Trials
The Bronx, New York, United States
Site recruitment: Not reported
Coastal Pediatric Research
Charleston, South Carolina, United States
Site recruitment: Not reported
Coastal Pediatric Research
Mt. Pleasant, South Carolina, United States
Site recruitment: Not reported
Clinical Research Partners, LLC
Richmond, Virginia, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 4UnknownINTERVENTIONAL

Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders

ClinicalTrials.gov · NCT05134584 · Registry updated: 2021-12-13

Condition / research focus: Functional Dyspepsia; Constipation-predominant Irritable Bowel Syndrome
Sponsor: RenJi Hospital
Countries with listed sites: China
Registry dates and results: Start: 2021-01-01. Completion: 2022-02 (may be estimated). No results posted in this registry response.

Products and interventions (4)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug) — also listed as: Linzess
Lactulose (drug) — also listed as: Duphalac
Omeprazol (drug)
Itopride (drug)

Where the study takes place — 1 listed sites

RenJiH
Shanghai, Shanghai Municipality, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 4TerminatedINTERVENTIONAL

A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)

ClinicalTrials.gov · NCT02837783 · Registry updated: 2021-12-06

Condition / research focus: Irritable Bowel Syndrome Characterized by Constipation
Sponsor: Ironwood Pharmaceuticals, Inc.
Countries with listed sites: United Kingdom
Registry dates and results: Start: 2016-12-21. Completion: 2018-10-31 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Peter Whorwell
Wythenshawe, Manchester, United Kingdom
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableUnknownINTERVENTIONAL

Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation

ClinicalTrials.gov · NCT05137145 · Registry updated: 2021-11-30

Condition / research focus: Bowel Preparation
Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University
Countries with listed sites: China
Registry dates and results: Start: 2021-09-01. Completion: 2022-04-30 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Compound Polyethylene Glycol Electrolyte Powder (drug)

Where the study takes place — 1 listed sites

The second affiliated hospital of xi'an jiaotong university
Xi'an, Shaanxi, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Not applicableWithdrawnINTERVENTIONAL

HygiRelief Procedure and HygiSample Evaluation for Functional Constipation

ClinicalTrials.gov · NCT04532879 · Registry updated: 2021-09-17

Condition / research focus: Rome IV Functional Constipation
Sponsor: HyGIeaCare, Inc.
Countries with listed sites: No country reported
Registry dates and results: Start: 2021-09. Completion: 2022-06 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

HygiPrep (HyGIeaCare System) (device) — also listed as: HygiSample (stool collection for microbiome evaluation)

Where the study takes place — 0 listed sites

The registry does not list facilities in this record. This does not mean the study has no sites.

Original record, eligibility, contacts and results →

Phase not reported / not applicableWithdrawnOBSERVATIONAL

Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation

ClinicalTrials.gov · NCT03342287 · Registry updated: 2021-08-31

Condition / research focus: Constipation; Irritable Bowel Syndrome
Sponsor: McMaster University
Countries with listed sites: Canada
Registry dates and results: Start: 2016-03. Completion: 2021-03 (may be estimated). No results posted in this registry response.

Products and interventions (4)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

questionnaires (other)
cognitive evaluation (other)
Blood (other)
Fecal sample (other)

Where the study takes place — 1 listed sites

McMaster University Medical Centre
Hamilton, Ontario, Canada
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 3UnknownINTERVENTIONAL

Evaluation of Clinical Equivalence Between Two Linaclotide Products in the Treatment of Chronic Idiopathic Constipation

ClinicalTrials.gov · NCT04804267 · Registry updated: 2021-03-18

Condition / research focus: Chronic Idiopathic Constipation
Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.
Countries with listed sites: China
Registry dates and results: Start: 2021-03-05. Completion: 2022-08-31 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
LINZESS® (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Renji Hospital, Medical Collge of Shanghai Jiaotong University
Shanghai, Shanghai Municipality, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 2TerminatedINTERVENTIONAL

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation

ClinicalTrials.gov · NCT02559817 · Registry updated: 2020-12-28

Condition / research focus: Irritable Bowel Syndrome With Constipation
Sponsor: Forest Laboratories
Countries with listed sites: Canada · United States
Registry dates and results: Start: 2015-11-01. Completion: 2019-08-30 (may be estimated). Results are posted in this registry.

Products and interventions (5)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide Dose A (drug) — also listed as: Linzess
Linaclotide Dose B (drug) — also listed as: Linzess
Linaclotide Dose C (drug) — also listed as: Linzess
Linaclotide Approved Adult Dose (drug) — also listed as: Linzess
Matching Placebo (drug) — also listed as: Linzess

Where the study takes place — 48 listed sites

HealthStar Research, LLC
Hot Springs, Arkansas, United States
Site recruitment: Not reported
Applied Research Center of Arkansas
Little Rock, Arkansas, United States
Site recruitment: Not reported
Advanced Research Center - Site 069
Anaheim, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
WCCT Global, LLC
Costa Mesa, California, United States
Site recruitment: Not reported
ACTCA, Inc
Los Angeles, California, United States
Site recruitment: Not reported
Children's Hospital Los Angeles
Los Angeles, California, United States
Site recruitment: Not reported
Center for Clinical Trials, LLC
Paramount, California, United States
Site recruitment: Not reported
University of California at San Francisco
San Francisco, California, United States
Site recruitment: Not reported
Advanced Medical Research Center
Miami, Florida, United States
Site recruitment: Not reported
Children's Center for Digestive Health Care LLC
Atlanta, Georgia, United States
Site recruitment: Not reported
Sleepcare Clinical Research Institute
Stockbridge, Georgia, United States
Site recruitment: Not reported
Methodist Medical Center
Peoria, Illinois, United States
Site recruitment: Not reported
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
Willis-Knighton Physician Network
Shreveport, Louisiana, United States
Site recruitment: Not reported
Certified Research Consultants Virgo/Carter Pediatrics
Silver Spring, Maryland, United States
Site recruitment: Not reported
GI Associates and Endoscopy Center
Jackson, Mississippi, United States
Site recruitment: Not reported
Children's Mercy Hospital
Kansas City, Missouri, United States
Site recruitment: Not reported
Boys Town National Research Hospital
Boys Town, Nebraska, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Goryeb Children's Hospital
Morristown, New Jersey, United States
Site recruitment: Not reported
Columbia University Medical Center and Morgan Stanley Children's Hospital of New York
New York, New York, United States
Site recruitment: Not reported
Asheboro Research Associates - Site 022
Asheboro, North Carolina, United States
Site recruitment: Not reported
Capital Pediatrics and Adolescent Center PLLC
Raleigh, North Carolina, United States
Site recruitment: Not reported
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Site recruitment: Not reported
Ohio Pediatric Research Association
Dayton, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
St. Christopher's Hospital for Children
Philadelphia, Pennsylvania, United States
Site recruitment: Not reported
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Preferred Primary Care Physicians, Inc.
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Frontier Clinical Research, LLC
Scottdale, Pennsylvania, United States
Site recruitment: Not reported
Montgomery Medical Inc.
Smithfield, Pennsylvania, United States
Site recruitment: Not reported
Rhode Island Hospital
Providence, Rhode Island, United States
Site recruitment: Not reported
Coastal Pediatric Research
Charleston, South Carolina, United States
Site recruitment: Not reported
Coastal Pediatrics Associates
Mt. Pleasant, South Carolina, United States
Site recruitment: Not reported
Cook Children's Medical Center
Fort Worth, Texas, United States
Site recruitment: Not reported
Texas Children's Hospital/Baylor College Medicine
Houston, Texas, United States
Site recruitment: Not reported
Houston Clinical Research Associates
Houston, Texas, United States
Site recruitment: Not reported
Sun Research Institute
San Antonio, Texas, United States
Site recruitment: Not reported
ClinPoint Trials
Waxahachie, Texas, United States
Site recruitment: Not reported
Children's Hospital of The King's Daughters
Norfolk, Virginia, United States
Site recruitment: Not reported
Virginia Tech Carilion School of Medicine Pediatric Gastroenterology
Roanoke, Virginia, United States
Site recruitment: Not reported
MultiCare Institute for Research and Innovation
Tacoma, Washington, United States
Site recruitment: Not reported
Aurora Health Care, Aurora Medical Center in Summit
Summit, Wisconsin, United States
Site recruitment: Not reported
Children's Hospital of Western Ontario
London, Ontario, Canada
Site recruitment: Not reported
Physician's Clinical Research Inc.
Vaughan, Ontario, Canada
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically

ClinicalTrials.gov · NCT02220348 · Registry updated: 2020-12-19

Condition / research focus: Breast Feeding; Constipation; Irritable Bowel Syndrome
Sponsor: Forest Laboratories
Countries with listed sites: United States
Registry dates and results: Start: 2014-07-31. Completion: 2019-05-31 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

linaclotide (drug) — also listed as: Linzess

Where the study takes place — 2 listed sites

University of Iowa
Iowa City, Iowa, United States
Site recruitment: Not reported
Digestive Disease Specialists Inc (DDSI)
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 3CompletedINTERVENTIONAL

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

ClinicalTrials.gov · NCT03573908 · Registry updated: 2020-12-01

Condition / research focus: Irritable Bowel Syndrome Characterized by Constipation
Sponsor: Ironwood Pharmaceuticals, Inc.
Countries with listed sites: United States
Registry dates and results: Start: 2018-06-20. Completion: 2019-04-10 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug) — also listed as: Linzess
Placebo (drug)

Where the study takes place — 79 listed sites

Clinical Research Associates
Huntsville, Alabama, United States
Site recruitment: Not reported
Elite Clinical Studies
Phoenix, Arizona, United States
Site recruitment: Not reported
Adobe Clinical Research, LLC
Tucson, Arizona, United States
Site recruitment: Not reported
Arkansas Gastroenterology
North Little Rock, Arkansas, United States
Site recruitment: Not reported
GW Research, Inc.
Chula Vista, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
Diagnamics, Inc.
Encinitas, California, United States
Site recruitment: Not reported
MD Studies, Inc.
Fountain Valley, California, United States
Site recruitment: Not reported
Paragon Rx Clinical, Inc. - Garden Grove
Garden Grove, California, United States
Site recruitment: Not reported
Grossmont Center For Clinical Research
La Mesa, California, United States
Site recruitment: Not reported
Facey Medical Foundation
Mission Hills, California, United States
Site recruitment: Not reported
Providence Clinical Research
North Hollywood, California, United States
Site recruitment: Not reported
Precision Research Institute
San Diego, California, United States
Site recruitment: Not reported
Paragon Rx Clinical, Inc.- Santa Ana
Santa Ana, California, United States
Site recruitment: Not reported
Millennium Clinical Trials
Thousand Oaks, California, United States
Site recruitment: Not reported
St. Joseph Heritage Healthcare
Yorba Linda, California, United States
Site recruitment: Not reported
Connecticut Clinical Research Institute
Bristol, Connecticut, United States
Site recruitment: Not reported
Chase Medical Research, LLC
Waterbury, Connecticut, United States
Site recruitment: Not reported
Clinical Research of South Florida
Coral Gables, Florida, United States
Site recruitment: Not reported
Avail Clinical Research, LLC
DeLand, Florida, United States
Site recruitment: Not reported
Palmetto Research, LLC
Hialeah, Florida, United States
Site recruitment: Not reported
Nature Coast Clinical Research, LLC
Inverness, Florida, United States
Site recruitment: Not reported
The Chappel Group Research
Kissimmee, Florida, United States
Site recruitment: Not reported
Jesscan Medical Research
Miami, Florida, United States
Site recruitment: Not reported
Well Pharma Medical Research Corporation
Miami, Florida, United States
Site recruitment: Not reported
New Horizon Research Center
Miami, Florida, United States
Site recruitment: Not reported
San Marcus Research Clinic, Inc.
Miami Lakes, Florida, United States
Site recruitment: Not reported
Ocean Blue Medical Research Center, Inc.
Miami Springs, Florida, United States
Site recruitment: Not reported
Ormond Medical Arts Pharmaceutical Research Center
Ormond Beach, Florida, United States
Site recruitment: Not reported
Precision Clinical Research
Sunrise, Florida, United States
Site recruitment: Not reported
Meridien Research - Tampa
Tampa, Florida, United States
Site recruitment: Not reported
Palm Beach Research Center
West Palm Beach, Florida, United States
Site recruitment: Not reported
Research Institute of Central Florida, LLC
Winter Park, Florida, United States
Site recruitment: Not reported
Mount Vernon Clinical Research, LLC
Sandy Springs, Georgia, United States
Site recruitment: Not reported
Clinical Trials Management, LLC
Metairie, Louisiana, United States
Site recruitment: Not reported
Delta Research Partners, LLC
Monroe, Louisiana, United States
Site recruitment: Not reported
Louisiana Research Center, LLC
Shreveport, Louisiana, United States
Site recruitment: Not reported
Alan A. Rosen, MD, PA
Baltimore, Maryland, United States
Site recruitment: Not reported
Meritus Center For Clinical Research
Hagerstown, Maryland, United States
Site recruitment: Not reported
Boston Clinical Trials, Inc.
Boston, Massachusetts, United States
Site recruitment: Not reported
MedVadis Research Corporation
Watertown, Massachusetts, United States
Site recruitment: Not reported
Gastroenterology Associates of West Michigan
Wyoming, Michigan, United States
Site recruitment: Not reported
Gastrointestinal Associates PA
Flowood, Mississippi, United States
Site recruitment: Not reported
St. Louis Center For Clinical Research
St Louis, Missouri, United States
Site recruitment: Not reported
Bozeman Health Deaconess Hospital
Bozeman, Montana, United States
Site recruitment: Not reported
Clinical Research of South Nevada
Las Vegas, Nevada, United States
Site recruitment: Not reported
Healthwise Medical Associates
Brooklyn, New York, United States
Site recruitment: Not reported
Long Island Gastrointestinal Research Group, LLP
Great Neck, New York, United States
Site recruitment: Not reported
Carolina Digestive Health Associates
Charlotte, North Carolina, United States
Site recruitment: Not reported
Carolina Digestive Health Associates
Concord, North Carolina, United States
Site recruitment: Not reported
Cumberland Research Associates
Fayetteville, North Carolina, United States
Site recruitment: Not reported
Peters Medical Research, LLC
High Point, North Carolina, United States
Site recruitment: Not reported
Wake Research Associates, LLC
Raleigh, North Carolina, United States
Site recruitment: Not reported
PMG Research of Wilmington
Wilmington, North Carolina, United States
Site recruitment: Not reported
Clinical Trials of America - North Carolina, LLC
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
Lyndhurst Clinical Research
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
PMG Research of Winston-Salem
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
Lillestol Research
Fargo, North Dakota, United States
Site recruitment: Not reported
Hightop Medical Research Center
Cincinnati, Ohio, United States
Site recruitment: Not reported
New Horizons Clinical Research
Cincinnati, Ohio, United States
Site recruitment: Not reported
Remington Davis, Inc.
Columbus, Ohio, United States
Site recruitment: Not reported
Dayton Gastroenterology, Inc.
Dayton, Ohio, United States
Site recruitment: Not reported
Hometown Urgent Care and Research
Dayton, Ohio, United States
Site recruitment: Not reported
Great Lakes Gastroenterology Research, LLC
Mentor, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
Partners In Clinical Research
Cumberland, Rhode Island, United States
Site recruitment: Not reported
Mountain View Clinical Research, Inc.
Greer, South Carolina, United States
Site recruitment: Not reported
Meridian Clinical Research
Dakota Dunes, South Dakota, United States
Site recruitment: Not reported
ClinSearch, LLC
Chattanooga, Tennessee, United States
Site recruitment: Not reported
New Phase Research & Development
Knoxville, Tennessee, United States
Site recruitment: Not reported
MW Clinical Research Center
Beaumont, Texas, United States
Site recruitment: Not reported
Southwest Clinical Trials
Houston, Texas, United States
Site recruitment: Not reported
Southwest Clinical Trials
Houston, Texas, United States
Site recruitment: Not reported
Quality Research, Inc.
San Antonio, Texas, United States
Site recruitment: Not reported
Diagnostics Research Group
San Antonio, Texas, United States
Site recruitment: Not reported
Stone Oak, LLC dba Discovery Clinical Trials
San Antonio, Texas, United States
Site recruitment: Not reported
Advanced Research Institute
Ogden, Utah, United States
Site recruitment: Not reported
New River Valley Research Institute
Christiansburg, Virginia, United States
Site recruitment: Not reported
Blue Ridge Medical Research
Lynchburg, Virginia, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

ClinicalTrials.gov · NCT02559206 · Registry updated: 2020-04-24

Condition / research focus: Irritable Bowel Syndrome With Constipation
Sponsor: Ironwood Pharmaceuticals, Inc.
Countries with listed sites: United States
Registry dates and results: Start: 2015-10-22. Completion: 2016-09-30 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug)
Matching Placebo (drug)

Where the study takes place — 71 listed sites

Ironwood Investigational Site
Huntsville, Alabama, United States
Site recruitment: Not reported
Ironwood Investigational Site
Phoenix, Arizona, United States
Site recruitment: Not reported
Ironwood Investigational Site
Tucson, Arizona, United States
Site recruitment: Not reported
Ironwood Investigational Site
North Little Rock, Arkansas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Anaheim, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chula Vista, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Garden Grove, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
La Mesa, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Newport Beach, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Orange, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Diego, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Thousand Oaks, California, United States
Site recruitment: Not reported
Ironwood Investigational Site
Colorado Springs, Colorado, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bristol, Connecticut, United States
Site recruitment: Not reported
Ironwood Investigational Site
Waterbury, Connecticut, United States
Site recruitment: Not reported
Ironwood Investigational Site
Hialeah, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Kissimmee, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Orlando, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
South Miami, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Tampa, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
West Palm Beach, Florida, United States
Site recruitment: Not reported
Ironwood Investigational Site
Atlanta, Georgia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Oakwood, Georgia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Sandy Springs, Georgia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Evansville, Indiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bastrop, Louisiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Metairie, Louisiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Shreveport, Louisiana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Baltimore, Maryland, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chevy Chase, Maryland, United States
Site recruitment: Not reported
Ironwood Investigational Site
Boston, Massachusetts, United States
Site recruitment: Not reported
Ironwood Investigational Site
Watertown, Massachusetts, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chesterfield, Michigan, United States
Site recruitment: Not reported
Ironwood Investigational Site
Wyoming, Michigan, United States
Site recruitment: Not reported
Ironwood Investigational Site
Jackson, Mississippi, United States
Site recruitment: Not reported
Ironwood Investigational Site
St Louis, Missouri, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bozeman, Montana, United States
Site recruitment: Not reported
Ironwood Investigational Site
Las Vegas, Nevada, United States
Site recruitment: Not reported
Ironwood Investigational Site
Las Vegas, Nevada, United States
Site recruitment: Not reported
Ironwood Investigational Site
Brooklyn, New York, United States
Site recruitment: Not reported
Ironwood Investigational Site
Charlotte, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Concord, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Davidson, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Fayetteville, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Wilmington, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
Ironwood Investigational Site
Cincinnati, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Cincinnati, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Mentor, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Xenia, Ohio, United States
Site recruitment: Not reported
Ironwood Investigational Site
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Ironwood Investigational Site
Dakota Dunes, South Dakota, United States
Site recruitment: Not reported
Ironwood Investigational Site
Bristol, Tennessee, United States
Site recruitment: Not reported
Ironwood Investigational Site
Chattanooga, Tennessee, United States
Site recruitment: Not reported
Ironwood Investigational Site
Knoxville, Tennessee, United States
Site recruitment: Not reported
Ironwood Investigational Site
Arlington, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Beaumont, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
El Paso, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Houston, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Antonio, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Antonio, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
San Antonio, Texas, United States
Site recruitment: Not reported
Ironwood Investigational Site
Ogden, Utah, United States
Site recruitment: Not reported
Ironwood Investigational Site
Sandy City, Utah, United States
Site recruitment: Not reported
Ironwood Investigational Site
Christiansburg, Virginia, United States
Site recruitment: Not reported
Ironwood Investigational Site
Lynchburg, Virginia, United States
Site recruitment: Not reported
Ironwood Investigational Site
La Crosse, Wisconsin, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 4CompletedINTERVENTIONAL

An Open-Label, Long-term Study to Assess the Immunogenicity of LINZESS® (Linaclotide) Administered Orally to Adult Participants With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation

ClinicalTrials.gov · NCT02590432 · Registry updated: 2019-08-22

Condition / research focus: Irritable Bowel Syndrome With Constipation; Chronic Idiopathic Constipation
Sponsor: Forest Laboratories
Countries with listed sites: United States
Registry dates and results: Start: 2015-11-01. Completion: 2018-02-05 (may be estimated). Results are posted in this registry.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Linaclotide (drug) — also listed as: LINZESS®

Where the study takes place — 79 listed sites

Pinnacle Research Group, LLC
Anniston, Alabama, United States
Site recruitment: Not reported
North Alabama Research Center, LLC
Athens, Alabama, United States
Site recruitment: Not reported
Alliance Clinical Research
Childersburg, Alabama, United States
Site recruitment: Not reported
G & L Research, LLC
Foley, Alabama, United States
Site recruitment: Not reported
Radiant Research, Inc.
Chandler, Arizona, United States
Site recruitment: Not reported
Radiant Research, Inc.
Scottsdale, Arizona, United States
Site recruitment: Not reported
Clinical Research Institute of Arizona, LLC
Surprise, Arizona, United States
Site recruitment: Not reported
Clinical Research Consortium
Tempe, Arizona, United States
Site recruitment: Not reported
Desert Sun Clinical Research, LLC.
Tucson, Arizona, United States
Site recruitment: Not reported
Preferred Research Partners, Inc.
Little Rock, Arkansas, United States
Site recruitment: Not reported
Applied Research Center of Arkansas
Little Rock, Arkansas, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
Global Clinical Trials LLC
Costa Mesa, California, United States
Site recruitment: Not reported
Diagnamics Inc
Encinitas, California, United States
Site recruitment: Not reported
MD Studies, Inc.
Fountain Valley, California, United States
Site recruitment: Not reported
Research Center of Fresno, Inc.
Fresno, California, United States
Site recruitment: Not reported
VVCRD Clinical Research
Garden Grove, California, United States
Site recruitment: Not reported
Facey Medical Foundation
Mission Hills, California, United States
Site recruitment: Not reported
Clinical Trials Research
Sacramento, California, United States
Site recruitment: Not reported
Northern California Research
Sacramento, California, United States
Site recruitment: Not reported
Artemis Institute for Clinical Research
San Diego, California, United States
Site recruitment: Not reported
Precision Research Institute
San Diego, California, United States
Site recruitment: Not reported
Empire Clinical Research
Upland, California, United States
Site recruitment: Not reported
Lynn Institute of Denver
Denver, Colorado, United States
Site recruitment: Not reported
ZASA Clinical Research
Boynton Beach, Florida, United States
Site recruitment: Not reported
Meridien Research
Bradenton, Florida, United States
Site recruitment: Not reported
Clinical Research of Brandon LLC
Brandon, Florida, United States
Site recruitment: Not reported
Clinical Physiology Associates
Fort Myers, Florida, United States
Site recruitment: Not reported
Direct Helpers Research Center
Hialeah, Florida, United States
Site recruitment: Not reported
Eastern Research, Inc.
Hialeah, Florida, United States
Site recruitment: Not reported
Center for Advanced Gastroenterology
Maitland, Florida, United States
Site recruitment: Not reported
Florida Medical Center and Research, Inc.
Miami, Florida, United States
Site recruitment: Not reported
Clinical Neuroscience Solutions, Inc
Orlando, Florida, United States
Site recruitment: Not reported
Accord Clinical Research
Port Orange, Florida, United States
Site recruitment: Not reported
Meridien Research
St. Petersburg, Florida, United States
Site recruitment: Not reported
River Birch Research Alliance, LLC
Blue Ridge, Georgia, United States
Site recruitment: Not reported
North Georgia Clinical Research
Woodstock, Georgia, United States
Site recruitment: Not reported
Northwest Clinical Trials
Boise, Idaho, United States
Site recruitment: Not reported
Rockford Gastroenterology Associates
Rockford, Illinois, United States
Site recruitment: Not reported
Iowa Digestive Center, PC
Clive, Iowa, United States
Site recruitment: Not reported
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Site recruitment: Not reported
Integrated Clinical Trial Services, Inc.
West Des Moines, Iowa, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Newton, Kansas, United States
Site recruitment: Not reported
Health Science Research Center
Pratt, Kansas, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
KAMP Medical Research Inc
Natchitoches, Louisiana, United States
Site recruitment: Not reported
Coastal Research Associates, Inc.
South Weymouth, Massachusetts, United States
Site recruitment: Not reported
Bay State Clinical Trials, Inc.
Watertown, Massachusetts, United States
Site recruitment: Not reported
Aa Mrc Llc
Flint, Michigan, United States
Site recruitment: Not reported
Beyer Research
Kalamazoo, Michigan, United States
Site recruitment: Not reported
The Center for Clinical Trials, Inc.
Biloxi, Mississippi, United States
Site recruitment: Not reported
Sundance Clinical Research, LLC
St Louis, Missouri, United States
Site recruitment: Not reported
Digestive Health Associates
Reno, Nevada, United States
Site recruitment: Not reported
Albuquerque Clinical Trials
Albuquerque, New Mexico, United States
Site recruitment: Not reported
Lovelace Scientific Resources, Inc.
Albuquerque, New Mexico, United States
Site recruitment: Not reported
Drug Trials America
Hartsdale, New York, United States
Site recruitment: Not reported
Manhattan Medical Research Practice PLLC
New York, New York, United States
Site recruitment: Not reported
DiGiovanna Institute for Medical Education & Research
North Massapequa, New York, United States
Site recruitment: Not reported
UNC Health Care, University of North Carolina Medical Center, Memorial Hospital
Chapel Hill, North Carolina, United States
Site recruitment: Not reported
PharmQuest
Greensboro, North Carolina, United States
Site recruitment: Not reported
Northstate Clinical Research
Lenoir, North Carolina, United States
Site recruitment: Not reported
Digestive Health Specialists, PA
Winston-Salem, North Carolina, United States
Site recruitment: Not reported
New Horizons Clinical Research
Cincinnati, Ohio, United States
Site recruitment: Not reported
Clinical Inquest Center LTD
Dayton, Ohio, United States
Site recruitment: Not reported
Dayton Gastroenterology, Inc.
Dayton, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
The Clinical Trial Center, LLC
Jenkintown, Pennsylvania, United States
Site recruitment: Not reported
Temple University
Philadelphia, Pennsylvania, United States
Site recruitment: Not reported
Preferred Primary Care Physicians, INC
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Montgomery Medical, Inc.
Smithfield, Pennsylvania, United States
Site recruitment: Not reported
Partners In Clinical Research
Cumberland, Rhode Island, United States
Site recruitment: Not reported
Greenville Pharmaceutical Research, Inc.
Greenville, South Carolina, United States
Site recruitment: Not reported
Radiant Research, Inc.
Greer, South Carolina, United States
Site recruitment: Not reported
Clinical Neuroscience Solutions, Inc.
Memphis, Tennessee, United States
Site recruitment: Not reported
Houston Endoscopy & Research Center
Houston, Texas, United States
Site recruitment: Not reported
Research Across America
Plano, Texas, United States
Site recruitment: Not reported
Sun Research Institute
San Antonio, Texas, United States
Site recruitment: Not reported
Charlottesville Medical Research Center, LLC
Charlottesville, Virginia, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableTerminatedINTERVENTIONAL

Efficacy of Linaclotide to Senna for CIC

ClinicalTrials.gov · NCT02239510 · Registry updated: 2019-07-02

Condition / research focus: Chronic Idiopathic Constipation
Sponsor: TriHealth Inc.
Countries with listed sites: United States
Registry dates and results: Start: 2014-09. Completion: 2016-06 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Senna (drug) — also listed as: sennoside
Linzess (drug) — also listed as: Linaclotide

Where the study takes place — 1 listed sites

TriHealth
Cincinnati, Ohio, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

ClinicalTrials.gov · NCT02559570 · Registry updated: 2019-06-19

Condition / research focus: Functional Constipation in Children Ages 6-17 Years
Sponsor: Forest Laboratories
Countries with listed sites: Canada · United States
Registry dates and results: Start: 2015-11-03. Completion: 2018-05-29 (may be estimated). Results are posted in this registry.

Products and interventions (5)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Placebo (drug)
LIN Dose A (drug) — also listed as: LINZESS
LIN Dose B (drug) — also listed as: LINZESS
LIN Dose C (drug) — also listed as: LINZESS
LIN 145 µg (drug) — also listed as: LINZESS

Where the study takes place — 62 listed sites

HealthStar Research, LLC
Hot Springs, Arkansas, United States
Site recruitment: Not reported
Applied Research Center of Arkansas
Little Rock, Arkansas, United States
Site recruitment: Not reported
Advanced Research Center
Anaheim, California, United States
Site recruitment: Not reported
Kindred Medical Institute for Clinical Trials, LLC
Corona, California, United States
Site recruitment: Not reported
WCCT Global, LLC
Costa Mesa, California, United States
Site recruitment: Not reported
Ark Clinical Research
Long Beach, California, United States
Site recruitment: Not reported
ACTCA, Inc
Los Angeles, California, United States
Site recruitment: Not reported
Children's Hospital Los Angeles
Los Angeles, California, United States
Site recruitment: Not reported
Orange County Research Institute
Ontario, California, United States
Site recruitment: Not reported
Center for Clinical Trials, LLC
Paramount, California, United States
Site recruitment: Not reported
UCSD Rady Children's Hospital
San Diego, California, United States
Site recruitment: Not reported
University of California at San Francisco
San Francisco, California, United States
Site recruitment: Not reported
Ventura Clinical Trials
Ventura, California, United States
Site recruitment: Not reported
Colorado Springs Health Partners, HCP-Clinical Research, LLC
Colorado Springs, Colorado, United States
Site recruitment: Not reported
Nova Southeastern University
Fort Lauderdale, Florida, United States
Site recruitment: Not reported
Homestead Research Institute
Homestead, Florida, United States
Site recruitment: Not reported
RM Medical Research
Homestead, Florida, United States
Site recruitment: Not reported
Advanced Medical Research Center
Miami, Florida, United States
Site recruitment: Not reported
SCORE Physician Alliance, LLC
St. Petersburg, Florida, United States
Site recruitment: Not reported
Children's Center for Digestive Health Care LLC
Atlanta, Georgia, United States
Site recruitment: Not reported
Sleepcare Clinical Research Institute
Stockbridge, Georgia, United States
Site recruitment: Not reported
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, United States
Site recruitment: Not reported
Heartland Research Associates, LLC
Wichita, Kansas, United States
Site recruitment: Not reported
Kentucky Pediatric/ Adult Research
Bardstown, Kentucky, United States
Site recruitment: Not reported
Kosair Children's Hospital - Pediatric Clinical Research Unit
Louisville, Kentucky, United States
Site recruitment: Not reported
Michael W. Simon, MD, PSC
Nicholasville, Kentucky, United States
Site recruitment: Not reported
Willis-Knighton Physician Network
Shreveport, Louisiana, United States
Site recruitment: Not reported
University of Maryland Children's Hospital
Baltimore, Maryland, United States
Site recruitment: Not reported
Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported
University Of Minnesota
Minneapolis, Minnesota, United States
Site recruitment: Not reported
GI Associates and Endoscopy Center
Jackson, Mississippi, United States
Site recruitment: Not reported
Craig A. Speigel, MD
Bridgeton, Missouri, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Midwest Children Health Research Institute
Lincoln, Nebraska, United States
Site recruitment: Not reported
Goryeb Children's Hospital
Morristown, New Jersey, United States
Site recruitment: Not reported
Columbia University Medical Center and Morgan Stanley
New York, New York, United States
Site recruitment: Not reported
Asheboro Research Associates
Asheboro, North Carolina, United States
Site recruitment: Not reported
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Site recruitment: Not reported
Capital Pediatrics and Adolescent Center PLLC
Raleigh, North Carolina, United States
Site recruitment: Not reported
Ohio Pediatric Research Association
Dayton, Ohio, United States
Site recruitment: Not reported
IPS Research Company
Oklahoma City, Oklahoma, United States
Site recruitment: Not reported
Pediatric Care Specialists
Johnstown, Pennsylvania, United States
Site recruitment: Not reported
St. Christopher's Hospital for Children
Philadelphia, Pennsylvania, United States
Site recruitment: Not reported
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Preferred Primary Care Physicians, Inc.
Pittsburgh, Pennsylvania, United States
Site recruitment: Not reported
Frontier Clinical Research, LLC
Scottdale, Pennsylvania, United States
Site recruitment: Not reported
Montgomery Medical Inc.
Smithfield, Pennsylvania, United States
Site recruitment: Not reported
Rhode Island Hospital
Providence, Rhode Island, United States
Site recruitment: Not reported
Coastal Pediatric Research
Charleston, South Carolina, United States
Site recruitment: Not reported
Coastal Pediatrics Associates
Mt. Pleasant, South Carolina, United States
Site recruitment: Not reported
Cook Children's Medical Center
Fort Worth, Texas, United States
Site recruitment: Not reported
Texas Children's Hospital/Baylor College Medicine
Houston, Texas, United States
Site recruitment: Not reported
Houston Clinical Research Associates
Houston, Texas, United States
Site recruitment: Not reported
Sun Research Institute
San Antonio, Texas, United States
Site recruitment: Not reported
Southwest Children's Research Associates, P.A.
San Antonio, Texas, United States
Site recruitment: Not reported
ClinPoint Trials
Waxahachie, Texas, United States
Site recruitment: Not reported
Foothill Family Clinic South / J. Lewis Research, Inc.
Salt Lake City, Utah, United States
Site recruitment: Not reported
Pediatric Specialists of Virginia
Fairfax, Virginia, United States
Site recruitment: Not reported
Virginia Tech Carilion School of Medicine Pediatric
Roanoke, Virginia, United States
Site recruitment: Not reported
Seattle Children's Hospital
Seattle, Washington, United States
Site recruitment: Not reported
Stollery Children's Hospital
Edmonton, Alberta, Canada
Site recruitment: Not reported
Children's Hospital of Western Ontario
London, Ontario, Canada
Site recruitment: Not reported

Original record, eligibility, contacts and results →