European Union
Regulator: Not represented
not_approved
As of: 9/9/2026 · Temporal status not established
Regulatory context incomplete: regulator.
Scientific intelligence record
Experience 2.0
Synthetic regulatory peptide
Synthetic ACTH-fragment-derived heptapeptide studied chiefly in Russian-language neurobiology and clinical literature.
Record status
Traceability partial
Last meaningful update: 9/9/2026
Governed reviewed evidence
25
Governed records, not an efficacy score or total literature count.
Evidence boundary
0 / 25
Claim-linked support versus recorded evidence.
Research gaps
1
Unresolved questions remain visible.
Human experience
Below display gate
Observations never become clinical evidence.
Human experience · separate evidence stream
Eligible observations remain below the privacy and reliability threshold. WPF will not convert a handful of reports into a percentage, trend, or clinical claim.
Observation is valuable human context. It is not evidence of causation, efficacy, or safety.
Public display gate
n ≥ 20 eligible observations
Exact progress remains private before the threshold.
Intelligence snapshot
A compact view of what is represented, what remains unresolved, and how completely the record can be traced.
Governed reviewed evidence
25
Reviewed database records promoted through the governed publication workflow.
Contradictions
0
Conflicting evidence relationships that remain visible.
Research gaps
1
Questions the current record identifies as unresolved.
Connected media
0
Media records explicitly linked to this scientific record.
What we know
The project separates represented evidence from qualification, contradiction, uncertainty, and what the evidence does not establish.
This does not mean the scientific literature contains no findings. It means no reviewed institutional claim has been represented here.
Scientific context
Existing reviewed chemistry is preserved as scientific context. Chemistry and mechanism information do not establish clinical efficacy or safety.
Chemical identity describes the recorded molecular information. It does not establish biological activity, clinical efficacy, safety, or therapeutic suitability.
Explore further
Move from this peptide record into the project's broader evidence, research, comparison, and methodology systems.
Research
Chronology, unresolved research questions, opportunities, and researcher activity remain descriptive rather than evaluative.
2006 · study · Temporal status not established
Izvestiia Akademii nauk. Seriia biologicheskaia
2008 · study · Temporal status not established
Vestnik Rossiiskoi akademii meditsinskikh nauk
2010 · study · Temporal status not established
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova
2013 · study · Temporal status not established
Journal of molecular neuroscience : MN
Connections
Connections appear only when they are represented by the project’s underlying records.
institution
institution
institution
Traceability
The experience makes incomplete links visible instead of presenting a false impression of perfect provenance.
Source publication state
A governed source may be verified and approved for publication while its claim-to-evidence link is still incomplete.
Reviewer provenance state
“Human scientist reviewed: no” means that specific source-path attribution is not recorded. It does not silently negate the separate publication-review state.
Claim → Evidence
Incomplete
Evidence → Source
Connected
Source → Original record
Connected
Traceability documents how the project connects statements to records. It does not establish that a source is scientifically valid or that a claim is clinically true.
Incomplete links: claim-to-evidence
[The efficacy of semax in the tretament of patients at different stages of ischemic stroke].
Observational archive
Observational archive data is intentionally separated from published scientific evidence.
Observational boundary
Insufficient eligible observations are available for display under the current filters.
Insufficient eligible observations are currently represented to display aggregated findings for this peptide.
Regulatory context
Regulatory status is jurisdiction-specific and time-dependent. It is presented as context, not as a recommendation for use or a substitute for scientific evidence evaluation.
European Union
Regulator: Not represented
As of: 9/9/2026 · Temporal status not established
Regulatory context incomplete: regulator.
United States
Regulator: Not represented
As of: 9/9/2026 · Temporal status not established
Regulatory context incomplete: regulator.
Research + media
Only media explicitly linked through the project’s relationship system appears here.
No scientifically connected media is currently represented for this peptide.
Sources + provenance
Semax evidence · ranking key
A tier describes the evidentiary role and design strength of a source. It is not a popularity score, proof that every conclusion is correct, or a substitute for claim-level review.
Large, well-conducted randomized trials; prespecified major outcomes; rigorous systematic reviews or meta-analyses; and major regulatory assessments.
Smaller randomized trials, strong prospective cohorts, prespecified secondary analyses, and high-quality comparative-effectiveness studies.
Retrospective cohorts, claims-database studies, pharmacovigilance analyses, mechanistic human research, and well-documented case series.
Case reports, conference abstracts, preclinical research, hypothesis-generating analyses, and expert commentary.
Tier classifies source design and evidentiary role. Confidence reflects risk of bias, sample size, comparator quality, outcome relevance, follow-up, missing data, directness, replication, reporting quality, and whether conclusions stay within the measured results.
Governed scientific evidence
Duplicate-safe scientific sources under accountable human review. Identified or pending records do not contribute as approved evidence.
Audit view
Human and preclinical evidence remain separate. Source identity, claim-to-source traceability, review dates, conflicts, limitations, and unknowns stay visible rather than being collapsed into one score.
PubMed-indexed clinical trial; journal article examining [the efficacy of semax in the tretament of patients at different stages of ischemic stroke]. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; review examining therapeutic peptides in orthopaedics: applications, challenges, and future directions. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; research support, non-u.s. gov't; review examining pharmacological aspects of neuro-immune interactions. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; research support, non-u.s. gov't examining the influence of selank on the level of cytokines under the conditions of "social" stress. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; review examining [possible role of transthyretin in the biological mechanism of the regulatory peptide neuroprotection.]. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed comparative study; journal article; review examining [comparison of anticoagulant effects of regulatory proline-containing oligopeptides. specificity of glyprolines, semax, and selank and potential of their practical application]. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; review examining therapeutic peptides in gerontology: mechanisms and applications for healthy aging. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining influence of actg4-7-pgp (semax) on morphofunctional state of hepatocytes in chronic emotional and painful stress. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining correction of lipid metabolism disorders in diabetes mellitus with peptide drugs. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining [a comparative chemoreactome analysis of mexidol]. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; review examining sigmoidal maximal effect modeling of low-density lipoprotein cholesterol concentration and annual incidence of coronary heart disease events in secondary prevention trials. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed english abstract; journal article; review examining [evolution of the stress concept]. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed english abstract; journal article examining [nootropic and analgesic effects of semax following different routes of administration]. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining functional connectomic approach to studying selank and semax effects. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; research support, non-u.s. gov't examining effect of semax and its c-terminal fragment pro-gly-pro on the expression of vegf family genes and their receptors in experimental focal ischemia of the rat brain. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining brain protein expression profile confirms the protective effect of the acth(4-7)pgp peptide (semax) in a rat model of cerebral ischemia-reperfusion. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining semax, synthetic acth(4-10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining acth-like peptides compensate rat brain gene expression profile disrupted by ischemia a day after experimental stroke. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining semax, an analog of acth(4-7), regulates expression of immune response genes during ischemic brain injury in rats. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; research support, non-u.s. gov't examining the peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining genes that associated with action of acth-like peptides with neuroprotective potential in rat brain regions with different degrees of ischemic damage. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining the potential of the peptide drug semax and its derivative for correcting pathological impairments in the animal model of alzheimer's disease. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining semax peptide targets the μ opioid receptor gene oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article; research support, non-u.s. gov't examining novel insights into the protective properties of acth(4-7)pgp (semax) peptide at the transcriptome level following cerebral ischaemia-reperfusion in rats. Machine-staged source candidate; findings and limitations require accountable review before publication.
PubMed-indexed journal article examining [the peptide drug acth(4-7)pgp (semax) suppresses mrna transcripts encoding proinflammatory mediators induced by reversible ischemia of the rat brain]. Machine-staged source candidate; findings and limitations require accountable review before publication.
2014 · study · Temporal status not established
Pharmacotherapy
2014 · study · Temporal status not established
BMC genomics
2016 · study · Temporal status not established
Molekuliarnaia genetika, mikrobiologiia i virusologiia
2017 · study · Temporal status not established
Bulletin of experimental biology and medicine
2017 · study · Temporal status not established
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
2017 · study · Temporal status not established
Molecular genetics and genomics : MGG
2018 · study · Temporal status not established
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
2018 · study · Temporal status not established
Current pharmaceutical design
2020 · study · Temporal status not established
Bulletin of experimental biology and medicine
2020 · study · Temporal status not established
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections
2020 · study · Temporal status not established
Genes
2021 · study · Temporal status not established
Current reviews in clinical and experimental pharmacology
2021 · study · Temporal status not established
International journal of molecular sciences
2021 · study · Temporal status not established
Neuropeptides
2021 · study · Temporal status not established
Molekuliarnaia biologiia
2024 · study · Temporal status not established
Biomedicines
2025 · study · Temporal status not established
International journal of molecular sciences
2025 · study · Temporal status not established
Acta naturae
2025 · study · Temporal status not established
British journal of pharmacology
2026 · study · Temporal status not established
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
2026 · study · Temporal status not established
Frontiers in aging
2026 · regulatory · Temporal status not established
European Union
2026 · regulatory · Temporal status not established
United States
The represented chronology reflects records currently included in the governed dataset and does not claim to represent the entire scientific literature.
No institutional claim record is currently represented for this peptide.
Evidence is missing or not represented as studied; this is not a conclusion that the intervention does not work.
These are bibliographic author identities derived from represented records. Name strings are not proof of unique real-world researcher identity, and publishing organizations are not treated as institutional affiliations.
7 represented evidence records
Years represented: 2013, 2014, 2017, 2020, 2021, 2024, 2025
Publishing organizations appearing in records: BMC genomics, Biomedicines, Genes, International journal of molecular sciences, Journal of molecular neuroscience : MN, Molecular genetics and genomics : MGG
6 represented evidence records
Years represented: 2013, 2014, 2017, 2020, 2024, 2025
Publishing organizations appearing in records: BMC genomics, Biomedicines, Genes, International journal of molecular sciences, Journal of molecular neuroscience : MN, Molecular genetics and genomics : MGG
5 represented evidence records
Years represented: 2016, 2017, 2020, 2021, 2025
Publishing organizations appearing in records: Acta naturae, Bulletin of experimental biology and medicine, Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, Molekuliarnaia biologiia, Molekuliarnaia genetika, mikrobiologiia i virusologiia
5 represented evidence records
Years represented: 2013, 2014, 2017, 2024, 2025
Publishing organizations appearing in records: BMC genomics, Biomedicines, International journal of molecular sciences, Journal of molecular neuroscience : MN, Molecular genetics and genomics : MGG
5 represented evidence records
Years represented: 2013, 2014, 2017, 2020, 2021
Publishing organizations appearing in records: BMC genomics, Genes, International journal of molecular sciences, Journal of molecular neuroscience : MN, Molecular genetics and genomics : MGG
5 represented evidence records
Years represented: 2020, 2021, 2024, 2025
Publishing organizations appearing in records: Biomedicines, Genes, International journal of molecular sciences, Molekuliarnaia biologiia
4 represented evidence records
Years represented: 2020, 2021, 2024, 2025
Publishing organizations appearing in records: Biomedicines, Genes, International journal of molecular sciences
4 represented evidence records
Years represented: 2020, 2021, 2024, 2025
Publishing organizations appearing in records: Biomedicines, Genes, International journal of molecular sciences
4 represented evidence records
Years represented: 2010, 2016, 2017, 2025
Publishing organizations appearing in records: Acta naturae, Bulletin of experimental biology and medicine, Molekuliarnaia genetika, mikrobiologiia i virusologiia, Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova
4 represented evidence records
Years represented: 2020, 2021, 2024, 2025
Publishing organizations appearing in records: Biomedicines, Genes, International journal of molecular sciences
4 represented evidence records
Years represented: 2020, 2021, 2024, 2025
Publishing organizations appearing in records: Biomedicines, Genes, International journal of molecular sciences
3 represented evidence records
Years represented: 2013, 2014, 2017
Publishing organizations appearing in records: BMC genomics, Journal of molecular neuroscience : MN, Molecular genetics and genomics : MGG
institution
institution
institution
institution
institution
institution
institution
institution
institution
Claim: Not linked · Evidence: c255e920-d18b-5c70-80bb-ee6b1147afa8
PMID: 29798983 · DOI: 10.17116/jnevro20181183261-68
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Claim: Not linked · Evidence: 07626ecc-78cb-5384-9811-e4f1760f2a8d
PMID: 41490200 · DOI: 10.4155/fdd-2022-0009
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Pharmacological Aspects of Neuro-Immune Interactions.
Claim: Not linked · Evidence: 8ad559c2-8c7c-51a9-a14a-32847f30103a
PMID: 28875850 · DOI: 10.2174/1381612823666170829135115
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.
Claim: Not linked · Evidence: 4baa3019-37dc-51d0-b0d1-3982b9597563
PMID: 32621722 · DOI: 10.2174/1574884715666200704152810
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
[POSSIBLE ROLE OF TRANSTHYRETIN IN THE BIOLOGICAL MECHANISM OF THE REGULATORY PEPTIDE NEUROPROTECTION.].
Claim: Not linked · Evidence: 8668ff53-ba67-5851-b094-8cc49629e8da
PMID: 30383932 · DOI: Unavailable
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
[Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential of their practical application].
Claim: Not linked · Evidence: 77ec4e33-acf7-51cb-9423-5890a25296e6
PMID: 16634437 · DOI: Unavailable
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Claim: Not linked · Evidence: 6a5c195d-7228-55d8-a9fd-cb78fe3043ba
PMID: 42021992 · DOI: 10.1038/s41392-022-00904-4
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Influence of ACTG4-7-PGP (Semax) on Morphofunctional State of Hepatocytes in Chronic Emotional and Painful Stress.
Claim: Not linked · Evidence: 7d5a6464-fc4a-57fc-8fee-0dad0f081199
PMID: 28577097 · DOI: 10.1007/s10517-017-3748-4
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Correction of Lipid Metabolism Disorders in Diabetes Mellitus with Peptide Drugs.
Claim: Not linked · Evidence: 462233a5-9701-50e6-a8b1-d2abd259e8d3
PMID: 32246363 · DOI: 10.1007/s10517-020-04764-2
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
[A comparative chemoreactome analysis of mexidol].
Claim: Not linked · Evidence: af743379-242e-50a5-bc4f-fc1d727ff415
PMID: 28514338 · DOI: 10.17116/jnevro20171171275-84
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Sigmoidal maximal effect modeling of low-density lipoprotein cholesterol concentration and annual incidence of coronary heart disease events in secondary prevention trials.
Claim: Not linked · Evidence: 98772dbd-af5f-5a4d-b02b-56664527e413
PMID: 24877185 · DOI: 10.1002/phar.1368
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
[Evolution of the stress concept].
Claim: Not linked · Evidence: c4841809-5424-5e83-98b1-e310970a3374
PMID: 19140465 · DOI: Unavailable
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
[Nootropic and analgesic effects of Semax following different routes of administration].
Claim: Not linked · Evidence: 57fd7f9a-a078-525e-a934-3ca78437995d
PMID: 21268834 · DOI: Unavailable
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Functional Connectomic Approach to Studying Selank and Semax Effects.
Claim: Not linked · Evidence: 8cf0b4ac-e317-5aaf-88b7-1a593fff1775
PMID: 32342318 · DOI: 10.1134/S001249662001007X
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Effect of semax and its C-terminal fragment Pro-Gly-Pro on the expression of VEGF family genes and their receptors in experimental focal ischemia of the rat brain.
Claim: Not linked · Evidence: 7ead1d1d-c2ce-5e32-839c-6a9b908ee9a4
PMID: 22772900 · DOI: 10.1007/s12031-012-9853-y
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Brain Protein Expression Profile Confirms the Protective Effect of the ACTH(4-7)PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion.
Claim: Not linked · Evidence: d82f8a1c-86cf-5bd7-95f0-4a545b597d24
PMID: 34201112 · DOI: 10.32388/uq8dyz
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Semax, synthetic ACTH(4-10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats.
Claim: Not linked · Evidence: 30314958-dfed-57dc-bcd9-11241460b3a0
PMID: 33418449 · DOI: 10.1016/j.npep.2020.102114
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
ACTH-like Peptides Compensate Rat Brain Gene Expression Profile Disrupted by Ischemia a Day After Experimental Stroke.
Claim: Not linked · Evidence: ad23b59d-47f3-5ee4-b57a-25e119f98b5d
PMID: 39767736 · DOI: 10.1038/s41598-022-20623-8
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Semax, an analog of ACTH(4-7), regulates expression of immune response genes during ischemic brain injury in rats.
Claim: Not linked · Evidence: 18a81b90-9387-598d-8196-00d778d7e560
PMID: 28255762 · DOI: 10.1007/s00438-017-1297-1
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis.
Claim: Not linked · Evidence: 43665890-5958-52cf-a44e-cffcbde78b23
PMID: 24661604 · DOI: 10.1161/01.STR.12.6.723
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage.
Claim: Not linked · Evidence: 596dab1d-631d-511c-89ef-3819b3baebdd
PMID: 40650034 · DOI: 10.1101/gr.1239303
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
Claim: Not linked · Evidence: 3aba74a5-7e5c-577e-8f0d-8c6d513aadf4
PMID: 41479572 · DOI: 10.32607/actanaturae.27808
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.
Claim: Not linked · Evidence: 19fbe397-b63f-5152-938b-f18990cece78
PMID: 40692165 · DOI: 10.1111/bph.70122
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats.
Claim: Not linked · Evidence: 9b164437-b43d-567b-81b9-c63b64cf3b91
PMID: 32580520 · DOI: 10.1126/scitranslmed.aaf8732
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
[The Peptide Drug ACTH(4-7)PGP (Semax) Suppresses mRNA Transcripts Encoding Proinflammatory Mediators Induced by Reversible Ischemia of the Rat Brain].
Claim: Not linked · Evidence: 8e918b37-39f5-5cff-9631-90223ac2582a
PMID: 34097675 · DOI: 10.31857/S0026898421010043
Extraction: not-recorded · Review: verified · Source state: unknown
Machine extracted: no · Human scientist reviewed: no · Externally validated: no
Incomplete path: claim, extraction-status
Generated: 9/18/2026, 3:03:59 PM
Funding and conflicts are disclosed and considered, but sponsorship never automatically changes a tier. Corrections, retractions, and expressions of concern override the original rating.
Evidence searched through: Not recorded
Last accountable review: Not recorded
These are documentary and scientific-review signals, not conclusions of harm, ineffectiveness, safety, or absence of research.
This maturity index describes evidence-base development and governance. It is not a probability of efficacy, safety, truth, medical advice, or regulatory approval. Read the methodology.