{"schemaVersion":"wpf-profile-export-v1","exportedAt":"2026-09-18T15:30:51.384Z","profile":{"slug":"ghrp-2","name":"GHRP-2","aliases":[],"category":"Growth hormone secretagogue peptide"},"synthesis":{"mechanism":"Synthetic growth-hormone secretagogue and ghrelin-receptor agonist studied in endocrine challenge testing.","evidence":"Source identities are PubMed-resolved and provisionally graded by study design. Full-text findings, bias, applicability, contradictions, and regulatory interpretation remain pending.","safety":"Hormonal surrogate outcomes are not general evidence of health benefit; product and regulatory context matter.","observationalBoundary":"A minimum 25-source PubMed corpus and chemistry record are staged for accountable review. This profile remains suppressed until authorized scientific and publication approval.","openQuestions":"Which findings survive full-text risk-of-bias review? 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Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Natalia E Moskaleva; Pavel A Markin; Roman M Kuznetsov; Tatiana M Andronova; Svetlana A Appolonova","publishingOrg":"Biomedical chromatography : BMC","publicationYear":2020,"doi":"10.1002/bmc.4948","pubmedId":"32652605","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1002/bmc.4948","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1002/bmc.4948","pmid":"32652605","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"4da1ddc6-3708-5317-bc7b-ff4269edf9d7","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Detection of black market follistatin 344.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/31758732/","evidenceTier":"observational","summary":"PubMed-indexed journal article examining detection of black market follistatin 344. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Christian Reichel; Günter Gmeiner; Mario Thevis","publishingOrg":"Drug testing and analysis","publicationYear":2019,"doi":"10.1002/dta.2741","pubmedId":"31758732","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1002/dta.2741","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1002/dta.2741","pmid":"31758732","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"142528cd-35fa-5b9f-875c-b339bb0a02a2","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Glycine-modified growth hormone secretagogues identified in seized doping material.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/30136411/","evidenceTier":"observational","summary":"PubMed-indexed journal article examining glycine-modified growth hormone secretagogues identified in seized doping material. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Paulina Marta Gajda; Niels Bjerre Holm; Lars Jakobsen Hoej; Brian Schou Rasmussen; Petur Weihe Dalsgaard; Lotte Ask Reitzel; Kristian Linnet","publishingOrg":"Drug testing and analysis","publicationYear":2019,"doi":"10.1002/dta.2489","pubmedId":"30136411","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1002/dta.2489","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1002/dta.2489","pmid":"30136411","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"6c2397a6-2f0b-5096-907e-573f2ecf0028","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Analysis of new growth promoting black market products.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/29864719/","evidenceTier":"observational","summary":"PubMed-indexed journal article; research support, non-u.s. gov't examining analysis of new growth promoting black market products. 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Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Kazunori Kageyama; Satoru Sakihara; Wataru Kameda; Aya Sugiyama; Shinobu Takayasu; Ken Terui; Makoto Daimon","publishingOrg":"Endocrine journal","publicationYear":2018,"doi":"10.1507/endocrj.EJ17-0527","pubmedId":"29973439","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1507/endocrj.ej17-0527","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1507/endocrj.EJ17-0527","pmid":"29973439","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"7aa13bc4-4de2-52c2-807a-4475e1208cab","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/28830317/","evidenceTier":"observational","summary":"PubMed-indexed journal article examining growth hormone secretagogue treatment in hypogonadal men raises serum insulin-like growth factor-1 levels. 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Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Xiyao Zhang; Wensong Li; Ping Li; Manli Chang; Xu Huang; Qiang Li; Can Cui","publishingOrg":"BioMed research international","publicationYear":2014,"doi":"10.1155/2014/923564","pubmedId":"25247193","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1155/2014/923564","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article; Research Support, Non-U.S. Gov't"},"provenancePayload":{"doi":"10.1155/2014/923564","pmid":"25247193","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"7cd2ae37-01f4-5407-a966-8c2b45795467","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Metabolism of growth hormone releasing peptides.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/23101768/","evidenceTier":"observational","summary":"PubMed-indexed journal article; research support, non-u.s. gov't examining metabolism of growth hormone releasing peptides. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Andreas Thomas; Philippe Delahaut; Oliver Krug; Wilhelm Schänzer; Mario Thevis","publishingOrg":"Analytical chemistry","publicationYear":2012,"doi":"10.1021/ac302034w","pubmedId":"23101768","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1021/ac302034w","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article; Research Support, Non-U.S. Gov't"},"provenancePayload":{"doi":"10.1021/ac302034w","pmid":"23101768","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"4477d488-b21a-59e7-b0b5-4ea133d3b97f","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Growth hormone-releasing peptide-2 stimulates secretion and synthesis of adrenocorticotropic hormone in mouse pituitary.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/19682503/","evidenceTier":"animal","summary":"PubMed-indexed journal article; research support, non-u.s. gov't examining growth hormone-releasing peptide-2 stimulates secretion and synthesis of adrenocorticotropic hormone in mouse pituitary. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Kazunori Kageyama; Mihoko Kushibiki; Komaki Hanada; Satoru Sakihara; Minoru Yasujima; Toshihiro Suda","publishingOrg":"Regulatory peptides","publicationYear":2009,"doi":"10.1016/j.regpep.2009.07.018","pubmedId":"19682503","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1016/j.regpep.2009.07.018","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"animal_in_vivo","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article; Research Support, Non-U.S. Gov't"},"provenancePayload":{"doi":"10.1016/j.regpep.2009.07.018","pmid":"19682503","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"5b007447-8def-539d-8548-323f55fae015","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/17609397/","evidenceTier":"phase_1_2","summary":"PubMed-indexed controlled clinical trial; journal article; research support, non-u.s. gov't; validation study examining a simple diagnostic test using gh-releasing peptide-2 in adult gh deficiency. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Kazuo Chihara; Akira Shimatsu; Naomi Hizuka; Toshiaki Tanaka; Yoshiki Seino; Yuzuru Katofor; KP-102 Study Group","publishingOrg":"European journal of endocrinology","publicationYear":2007,"doi":"10.1530/EJE-07-0066","pubmedId":"17609397","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1530/eje-07-0066","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"human_interventional","extractionPayload":{"sourceStrength":{"grade":"B","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Validation Study"},"provenancePayload":{"doi":"10.1530/EJE-07-0066","pmid":"17609397","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"ab58134e-0dd5-50db-8d91-0b55c7b076cf","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"KP-102 (growth hormone-releasing peptide-2) attenuates ischemia/reperfusion injury in isolated rat hearts.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/16773386/","evidenceTier":"animal","summary":"PubMed-indexed journal article examining kp-102 (growth hormone-releasing peptide-2) attenuates ischemia/reperfusion injury in isolated rat hearts. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Sadayoshi Furuta; Toshimitsu Hori; Tadashi Ohyama","publishingOrg":"Naunyn-Schmiedeberg's archives of pharmacology","publicationYear":2006,"doi":"10.1007/s00210-006-0079-9","pubmedId":"16773386","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1007/s00210-006-0079-9","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"animal_in_vivo","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1007/s00210-006-0079-9","pmid":"16773386","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"19bdc25a-9c08-500e-9c34-9c1e5a8b5b8e","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"ACTH releasing activity of KP-102 (GHRP-2) in rats is mediated mainly by release of CRF.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/15645295/","evidenceTier":"animal","summary":"PubMed-indexed journal article examining acth releasing activity of kp-102 (ghrp-2) in rats is mediated mainly by release of crf. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Chiharu Hirotani; Yutaka Oki; Kiyoharu Ukai; Tadashi Okuno; Shigeru Kurasaki; Tadashi Ohyama; Naomi Doi; Ken Sasaki; Katsuhiko Ase","publishingOrg":"Naunyn-Schmiedeberg's archives of pharmacology","publicationYear":2005,"doi":"10.1007/s00210-004-1009-3","pubmedId":"15645295","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1007/s00210-004-1009-3","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"animal_in_vivo","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1007/s00210-004-1009-3","pmid":"15645295","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"9d56a3a2-0811-587c-9941-b873317bb984","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/15699539/","evidenceTier":"observational","summary":"PubMed-indexed journal article; research support, u.s. gov't, p.h.s. examining growth hormone releasing peptide-2 (ghrp-2), like ghrelin, increases food intake in healthy men. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Blandine Laferrère; Cynthia Abraham; Colleen D Russell; Cyril Y Bowers","publishingOrg":"The Journal of clinical endocrinology and metabolism","publicationYear":2005,"doi":"10.1210/jc.2004-1719","pubmedId":"15699539","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1210/jc.2004-1719","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article; Research Support, U.S. Gov't, P.H.S."},"provenancePayload":{"doi":"10.1210/jc.2004-1719","pmid":"15699539","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"455f178a-b291-5ada-bd30-20646a6e3fb7","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"General pharmacology of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/15646371/","evidenceTier":"observational","summary":"PubMed-indexed journal article examining general pharmacology of kp-102 (ghrp-2), a potent growth hormone-releasing peptide. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Sadayoshi Furuta; Osafumi Shimada; Naomi Doi; Kiyoharu Ukai; Terutake Nakagawa; Jyo Watanabe; Masakazu Imaizumi","publishingOrg":"Arzneimittel-Forschung","publicationYear":2004,"doi":"10.1055/s-0031-1297042","pubmedId":"15646371","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1055/s-0031-1297042","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1055/s-0031-1297042","pmid":"15646371","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"87cc88c2-2dd0-5309-86b7-55d13b765134","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Pharmacological characteristics of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/15646370/","evidenceTier":"observational","summary":"PubMed-indexed journal article examining pharmacological characteristics of kp-102 (ghrp-2), a potent growth hormone-releasing peptide. Machine-staged source candidate; findings and limitations require accountable review before publication.","authors":"Naomi Doi; Chiharu Hirotani; Kiyoharu Ukai; Osafumi Shimada; Tadashi Okuno; Shigeru Kurasaki; Takeshi Kiyofuji; Reiko Ikegami; Machiko Futamata; Terutake Nakagawa; Katsuhiko Ase; Kazuo Chihara","publishingOrg":"Arzneimittel-Forschung","publicationYear":2004,"doi":"10.1055/s-0031-1297041","pubmedId":"15646370","jurisdiction":null,"dateAccessed":"2026-09-09T11:42:47.093Z","editorialNotes":"Machine-staged candidate; no human approval asserted.","sourceType":"peer_reviewed_research","claimSupported":null,"supportNature":null,"qualification":null,"verificationStatus":"verified","publicationStatus":"published","addedById":null,"machineActor":"codex-governed-profile-batch-10-2026-09-09","reviewedById":"0bf5b853-ea8b-4aa3-bffe-2af0fdd75150","canonicalSourceIdentity":"doi:10.1055/s-0031-1297041","sourceIdentityId":null,"sourceStatus":"active","sourceContentHash":null,"sourceVersion":1,"retrievedAt":"2026-09-09T11:42:47.093Z","retrievalProvider":"NCBI PubMed","retrievalPayloadRef":null,"evidenceLane":"mechanistic","extractionPayload":{"sourceStrength":{"grade":"C","version":"WPF-ESR-1.0","provisional":true},"publicationTypes":"Journal Article"},"provenancePayload":{"doi":"10.1055/s-0031-1297041","pmid":"15646370","provider":"NCBI PubMed"},"validationGates":{"pmidResolved":true,"humanReviewed":false,"identityResolved":true,"publicationApproved":false},"engineState":"candidate","engineRunId":null,"createdAt":"2026-09-09T11:42:47.093Z","updatedAt":"2026-09-09T19:33:05.147Z"},{"id":"1d215325-5fa3-5793-8400-f42ead68f5fb","peptideId":"85f9bc7c-6257-44b5-b7b0-3f7f194ee1cd","title":"Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN.","sourceUrl":"https://pubmed.ncbi.nlm.nih.gov/15230633/","evidenceTier":"observational","summary":"PubMed-indexed journal article; review examining pralmorelin: ghrp 2, gpa 748, growth hormone-releasing peptide 2, kp-102 d, kp-102 ln, kp-102d, kp-102ln. 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